08 February 2025 : Clinical Research
Immune Dysregulation in Acute Herpes Zoster: Predictive Factors for Postherpetic Neuralgia
Meidi Wang BCDE 1, Yanrong Yuan BCDE 1, Jun Wang ABCF 1, Yongxing Yan ACDFG 1*, Huiqin Yu ABEF 2DOI: 10.12659/MSM.944688
Med Sci Monit 2025; 31:e944688
Table 2 Comparison of humoral and cellular immune function between 2 groups.
| HZ group (n=188) | Control group (n=79) | t | P | |
|---|---|---|---|---|
| Humoral immune status | ||||
| C3 (g/L) | 1.2±0.2 | 1.1±0.2 | 1.401 | 0.0922 |
| C4 (g/L) | 0.4±0.2 | 0.4±0.1 | 0.1769 | 0.8597 |
| IgA (g/L) | 2.4±1.0 | 2.2±1.0 | 0.0261 | 0.9792 |
| IgG (g/L) | 11.9±3.0 | 12.7±5.1 | 0.2516 | 0.8015 |
| IgM (g/L) | 1.0±0.7 | 0.9±0.5 | 1.209 | 0.2278 |
| Cellular immune status | ||||
| CD3+ (×10L) | 997.4±467.2 | 1192.3±397.0 | 3.243 | 0.0013 |
| CD19+ (×10/L) | 193.7±134.9 | 216.0±137.0 | 1.221 | 0.2232 |
| CD8+ (×10/L) | 391.4±239.3 | 391.0±189.5 | 0.0127 | 0.9899 |
| CD4+ (×10/L) | 543.4±285.9 | 745.7±273.9 | 5.336 | 0.0001 |
| CD56+ (×10/L) | 261.2±153.5 | 290.0±188.0 | 1.304 | 0.1933 |
| CD4+/CD8+ | 1.8±1.1 | 2.3±1.4 | 3.654 | 0.0023 |