Trends in HIV/AIDS-Related Mortality and the Impact of Antiretroviral Treatment Strategies in Lu'an City: A Comprehensive Analysis

Rui Shu; Haili Lyu; Gongyan Ma; Haiyan Chen; Yu Zhou; Jiaojiao Zhou; Jin Chen; Quanzhi Wang

doi:10.12659/MSM.944727

23 July 2024 : Database Analysis

Trends in HIV/AIDS-Related Mortality and the Impact of Antiretroviral Treatment Strategies in Lu'an City: A Comprehensive Analysis

Rui Shu^12ABCE, Haili Lyu^3ABCD, Gongyan Ma^2ABCDG*, Haiyan Chen^2ABC, Yu Zhou^2ABD, Jiaojiao Zhou^2BCF, Jin Chen^2DG, Quanzhi Wang^2BC

DOI: 10.12659/MSM.944727

Med Sci Monit 2024; 30:e944727

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Table 1 HIV/AIDS-related fatality rates: Univariate analysis.

Variables	Number of cases	Number of deaths	Fatality rate (%)	χ2	P value
Gender
Male	1994	339	17.00	0.219	0.640
Female	487	77	15.81
Age at diagnosis (years)
<15	26	8	30.77	89.207	<0.001
15~	296	17	5.74
25~	786	95	12.09
40~	875	147	16.80
60~	304	83	27.30
70~	185	66	35.68
Education Level
Primary school and below	881	210	23.84	51.063	<0.001
Junior high school	884	131	14.82
High school	396	51	12.88
College or above	311	24	7.72
Marital status
Married with spouse	1085	182	16.77	25.120	<0.001
Unmarried	769	95	12.35
Divorced or widowed	612	138	22.55
Unknown	6	1	16.67
Route of infection
Blood donation/plasma	8	3	37.50	131.258	<0.001
Blood transfusion/blood products	48	30	62.50
Mother-to-child transmission	23	6	26.09
Heterosexual transmission	1557	298	19.14
Homosexual transmission	807	68	8.43
Drug use	8	3	37.50
Unknown/other	21	8	38.10
CD4 count at diagnosis (cells/ul)
Not tested^*	206	189	91.75	635.979	<0.001
<50	323	84	26.01
50~	514	69	13.42
200~	636	37	5.82
350~	793	37	4.67
Last CD4 count (cells/ul)
Not tested^*	206	189	91.75	1101.784	<0.001
<50	128	74	57.81
50~	286	71	24.83
200~	498	48	9.64
350~	1354	34	2.51
ART
Yes	2197	222	10.10	637.903	<0.001
No	275	194	70.55
Year of diagnosis
Before 2007	55	32	58.18	99.969	<0.001
2007–2016	731	174	23.80
After 2017	1686	210	12.46
^* These patients died before CD4 count testing due to severe illness or non-compliance.

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Trends in HIV/AIDS-Related Mortality and the Impact of Antiretroviral Treatment Strategies in Lu'an City: A Comprehensive Analysis

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