22 July 2024 : Clinical Research
Comparative Analysis of Antihypertensive and Anticonvulsant Regimens in Managing Pre-eclampsia and Eclampsia: Insights from a Sudanese Retrospective Study
Qusay O. Abdalla
12ABCDEF, Esraa O. Mohammed 23ABCDEFG, Wajid Syed 4ABCDEFG, Ayesha Iqbal56ACFG, Mahmood Basil A. Al-Rawi7BCFG, Bashir A. Yousef 8ABCDEF*
DOI: 10.12659/MSM.944985
Med Sci Monit 2024; 30:e944985
Table 4 Antihypertensive regimens used before delivery and their effect on blood pressure.
| Regiment of treatment used before delivery | Blood pressure on admission | Blood pressure before delivery | P value | ||||
|---|---|---|---|---|---|---|---|
| Systolic | Diastolic | Systolic | Diastolic | Systolic | Diastolic | ||
| No drug (n=80) | 147±27.9 | 93.7±21.2 | 141±25.8 | 87.9±18 | .017 | .008 | |
| One drug | Nifedipine (n=15) | 162.6±23.3 | 102.7±14.6 | 146.7±14.9 | 94.2±11.3 | .003 | .062 |
| Hydralazine (n=26) | 176.6±28.5 | 109.3±17.9 | 152.9±24.3 | 97.6±15.9 | .002 | .016 | |
| Labetalol (n=3) | 176.3±35.5 | 108.6±28.7 | 163±35.3 | 98.7±28 | .423 | .423 | |
| Methyldopa (n=4) | 142.5±5 | 102.2±4.5 | 146±4.7 | 96.00±9.6 | .155 | .161 | |
| Two drugs | Hydralazine+ Nifedipine (n=29) | 171.9±24.8 | 116.2±23.3 | 156.1±21.1 | 102.8±23 | .014 | .016 |
| Nifedipine+ Methyldopa (n=8) | 159.8±21.3 | 98.4±8.3 | 149±27.01 | 90±15.8 | .203 | .300 | |
| Hydralazine+ Methyldopa (n=4) | 167.5±22.2 | 113.2±20.5 | 152±17.8 | 103.5±21.8 | .361 | .657 | |
| Three drugs | Hydralazine+Nifedipine+ Methyldopa (n=2) | 166.3±20.9 | 122.2±10.5 | 155.7±25.9 | 102.2±22.1 | .719 | .070 |
| Significant among treatment regimens | .001 | .001 | .008 | .052 | |||