22 July 2024 : Clinical Research
Comparative Analysis of Antihypertensive and Anticonvulsant Regimens in Managing Pre-eclampsia and Eclampsia: Insights from a Sudanese Retrospective Study
Qusay O. Abdalla
12ABCDEF, Esraa O. Mohammed 23ABCDEFG, Wajid Syed 4ABCDEFG, Ayesha Iqbal56ACFG, Mahmood Basil A. Al-Rawi7BCFG, Bashir A. Yousef 8ABCDEF*
DOI: 10.12659/MSM.944985
Med Sci Monit 2024; 30:e944985
Table 5 Postpartum antihypertensive regimens used and their effect on blood pressure.
| Regiment of treatment after delivery | Blood pressure after delivery | Blood pressure 2 days postpartum | P-value | ||||
|---|---|---|---|---|---|---|---|
| Systolic | Diastolic | Systolic | Diastolic | Systolic | Diastolic | ||
| No drug (n=56) | 129±15 | 80.7±13.4 | 123.9±14.9 | 78.1±13.1 | .078 | .262 | |
| One drug | Nifedipine (n=39) | 141.3±18.1 | 87.8±13.5 | 136.3±19.3 | 85.8±13 | .117 | .370 |
| Hydralazine (n=3) | 151.5±16.2 | 96±12.7 | 126.5±9.1 | 88±11.3 | .397 | .079 | |
| Atenolol (n=6) | 147.4±8 | 94.8±17.7 | 145.6±14 | 93.6±9.8 | .717 | .807 | |
| Amlodipine (n=19) | 141.4±13.3 | 88.3±9.2 | 133.7±10.7 | 83.7±9.9 | .077 | .237 | |
| Two drugs | Amlodipine+ Atenolol (n=10) | 144.1±23.2 | 93.4±20 | 142.7±21.2 | 91.1±16.3 | .843 | .747 |
| Nifedipine+ Amlodipine (n=10) | 143.5±12.6 | 90±9 | 132.5±52.9 | 80.8±15.4 | .495 | .187 | |
| Nifedipine+ Atenolol (n=9) | 157.3±18.1 | 104.1±12 | 140.6±14.5 | 89.1±12.6 | .012 | .001 | |
| Three drugs | Hydralazine+Nifedipine+ Atenolol (n=4) | 167.2±10.9 | 109±8.6 | 164.2±21.9 | 112.7±22.6 | .698 | .690 |
| Nifedipine+Amlodipine+ Atenolol (n=9) | 159.1±11.7 | 99.4±16.8 | 143.1±19.9 | 97±13.7 | .082 | .466 | |
| Hydralazine+Nifedipine+ Amlodipine (n=4) | 165.±21.2 | 104.6±11 | 138.5±2.1 | 95.6±7.5 | .355 | .501 | |
| Significant among treatment regimens | .001 | .001 | .055 | .001 | |||