Oxidative and Antioxidative Biomarker Profiles in Neonatal Hypoxic-Ischemic Encephalopathy: Insights for Pathophysiology and Treatment Strategies

17 August 2024 : Clinical Research

Nur Aycan^1ABCDEFG*, Derya Çay Demir^2ABDF, Eyyüp Yürektürk^3BFG, Murat Başaranoğlu^3DFG, Serap Karaman^3BFG, Oğuz Tuncer^3BDG

DOI: 10.12659/MSM.945045

Med Sci Monit 2024; 30:e945045

Introduction Material and Methods Results Discussion Conclusions References

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Table 1 Demographic and clinical features of newborns with hypoxia and healthy newborns.

Variables	HIE (n=59)	Control (n=32)	P value
Female^*	27 (45.7%)	16 (50%)	0.69
Type of delivery (vaginal)^*	38 (64.4%)	20 (62.5%)	0.47
Birth weight (g)^**	3019.2±58.72	3006.2±97.39	0.89
Gestational age (weeks)^**	38.77±0.14	38.19±0.18	0.6
Maternal age (years)^**	32.33±0.87	31.13±1.65	0.49
APGAR score 1 min^***	3 (1)	8 (2)	0.0001
APGAR score 5 min^***	6 (2)	9 (2)	0.0001
APGAR score 10 min^***	6 (2)	9 (1)	0.0001
Mortality^*	4 (6.7%)	–	0.0001
^* Chi-square; ^ mean±SEM; ^* median (IQR). HIE – hypoxic-ischemic encephalopathy.

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