17 August 2024 : Clinical Research
Oxidative and Antioxidative Biomarker Profiles in Neonatal Hypoxic-Ischemic Encephalopathy: Insights for Pathophysiology and Treatment Strategies
Nur Aycan1ABCDEFG*, Derya Çay Demir2ABDF, Eyyüp Yürektürk3BFG, Murat Başaranoğlu3DFG, Serap Karaman3BFG, Oğuz Tuncer3BDGDOI: 10.12659/MSM.945045
Med Sci Monit 2024; 30:e945045
Table 3 Catalase (CAT), glutathione (GSH), malondialdehyde (MDA), and ischemia-modified albumin (IMA) levels were not statistically significant between sexes in newborns with hypoxia (n=59).
| Parameter (n=59) | Female (n=27)* | Male (n=32)* | P value** |
|---|---|---|---|
| CAT (U/L) | 743.6±184.9 | 1138.48±198.1 | 0.37 |
| GSH (mmol/L) | 0.0039±0.0007 | 0.0033±0.0004 | 0.58 |
| MDA (mmol/mg) | 1.085±0.011 | 1.080±0.012 | 0.59 |
| IMA (U/mL) | 0.38±0.008 | 0.408±0.011 | 0.12 |
| * Mean±SEM; ** Mann-Whitney U test. CAT – catalase; GSH – glutathione; MDA – malondialdehyde; IMA – ischemia-modified albumin. | |||