Butorphanol Tartrate Nasal Spray for Post-Cesarean Analgesia and Prolactin Secretion

21 January 2025 : Clinical Research

Jingzheng Zeng^1ABCDEF, Xiaoqin Sun^1BDEF, Mingyan Luo^2BDF, Yunju Rao^1DF, Gu Gong^1AG*

DOI: 10.12659/MSM.945224

Med Sci Monit 2025; 31:e945224

Introduction Material and Methods Results Discussion Conclusions References

Related articles Order reprints Share article Share by email

View HTML version

Table 2 VAS scores, Ramsay scores, number of PCIA presses, and butorphanol consumption.

Variable	Postoperative time	Control (n=40)	BI (n=40)	BV (n=40)
VAS score	6 h	4 (3–4) [2–5]	3 (2–3) [1–4]^a	3 (2–3) [1–5]^a
	12 h	3 (3–3.25) [2–5]	3 (2–3) [1–4]	2 (2–3) [1–4]^a
	24 h	2 (2–3) [2–4]	2 (2–3) [1–3]	2 (2–2) [1–4]
Ramsay score	6 h	4 (2–3) [1–4]	4 (3–4) [1–5]^a	4 (3–4) [1–5]^a
	12 h	4 (3–5) [2–5]	4 (3–5) [2–5]	5 (4–5) [2–5]^a
	24 h	2 (2–2) [1–2]	2 (2–2) [2–3]	2 (2–2) [2–3]
PCIA presses (n)	6 h	3 (3–3) [0–6]	1 (0–2) [0–4]^a	2 (2–3) [0–5]^b
	12 h	2 (1–2) [0–5]	2 (1–3) [0–6]	1 (1–2) [0–3]^a
	24 h	1 (0–2) [0–10]	0 (0–1) [0–4]	0 (0–1) [0–3]
Butorphanol consumption (mL)	6 h	–	1.00 (1.00–1.00) [1.00–1.00]	1.2 (1.20–1.35) [0.90–1.65]b
Data are presented as median (interquartile range) [minimum and maximum] or percentage (proportion). ^a ^b Comparisons were performed using the Kruskal-Wallis test. VAS – visual analog scale; RASS – Ramsay Sedation Scale; PCIA – patient-controlled intravenous analgesia.

Back to the Article