15 November 2024 : Clinical Research
Adipose-Derived Mesenchymal Stem Cells from Arthritis Patients: Differential Modulation of CD4⁺ T Cell Activation and Cytokine Production
Maciej Ołdak1BC, Weronika Kurowska
1DE, Magdalena Plebańczyk1BE, Iwona Janicka1B, Anna Radzikowska 1CE, Urszula Skalska 1AFG, Ewa Kuca-Warnawin 1ABCDEF*
DOI: 10.12659/MSM.945273
Med Sci Monit 2024; 30:e945273
Table 1 Demographic and clinical characteristics of the patients.
| Rheumatoid arthritis (RA) (n=26) | Osteoarthritis (OA) (n=22) | |
|---|---|---|
| Demographics | ||
| Age, years | 60 (39–68) | 64 (39–69) |
| Sex, female (F)/male (M), n | 16F/8M | 17F/5M |
| BMI kg/m | 26,3 (18,0–37,1) | 32.33 (25,1–45.5)# |
| Laboratory values | ||
| CRP, mg/L | 20 (3–81) | 5 (2–32)## |
| ESR, mm/h | 30.5 (2–107) | 12 (1–38)# |
| Medications, % | ||
| Methotrexate | 53% | 0% |
| Glucocorticosteroids | 66% | 0% |
| Sulfasalazine | 33% | 0% |
| NSAIDs | 66% | 80% |
| Except where indicated otherwise, values are the median (min-max). BMI – body mass index; CRP – C-reactive protein; ESR – erythrocyte sedimentation rate;. # =0.05–0.01, and ## =0.01–0.001 for RA vs OAc comparisons. | ||