Enhanced Differentiation of Amiodarone-Induced Thyrotoxicosis Types Using Semi-Quantitative 99mTc-MIBI Uptake Analysis: A Pilot Study

Leo Fischer; Neva Girotto; Maja Ilić Tomaš; Martina Mavrinac; Andrica Lekić; Dragana Antončić; Tatjana Bogović Crnčić

doi:10.12659/MSM.945444

25 September 2024 : Clinical Research

Enhanced Differentiation of Amiodarone-Induced Thyrotoxicosis Types Using Semi-Quantitative 99mTc-MIBI Uptake Analysis: A Pilot Study

Leo Fischer^1BDEF, Neva Girotto^1DE*, Maja Ilić Tomaš^1BDE, Martina Mavrinac

^2CD, Andrica Lekić^3CD, Dragana Antončić

^4BD, Tatjana Bogović Crnčić^1ADE

DOI: 10.12659/MSM.945444

Med Sci Monit 2024; 30:e945444

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Table 2 The correlation between visual analysis and target-to-background ratio of 99mTc-Methoxy-2-Isobutylisonitrile (MIBI) uptake results using the mediastinal and supraclavicular regions of interest in all amiodarone-induced thyrotoxicosis groups.

Pair of variablesN=36	Spearman (rs)	P-value
Visual & TBR mediastinal ROI	0.34	0.043
Visual & TBR supraclavicular ROI	0.24	0.148
TBR – target-to-background ratio; ROI – region of interest.

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Enhanced Differentiation of Amiodarone-Induced Thyrotoxicosis Types Using Semi-Quantitative 99mTc-MIBI Uptake Analysis: A Pilot Study

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