01 January 2025 : Review article
Impact of Liver Disease on Use of Muscle Relaxants in Anesthesia: A Comprehensive Review
Paweł RadkowskiDOI: 10.12659/MSM.945822
Med Sci Monit 2025; 31:e945822
Table 2 Grade stages of ACLF depending on disease severity.
| Grade of ACLF | Criteria |
|---|---|
| Grade 1 | Single renal failure or single liver, coagulation, circulatory, or lung failure that is associated with a serum creatinine level of 1.5 to 1.9 mg/dL and/or hepatic encephalopathy grade 1 or grade 2 or a single brain failure with a serum creatinine level of 1.5 to 1.9 mg/dl |
| Grade 2 | Two organ failures of any combination |
| Grade 3 | Three or more organ failures of any combination |
| ACLF – acute-on-chronic liver failure. | |






