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14 November 2024 : Clinical Research  

Risk Factors for Bone Cement Displacement After Percutaneous Kyphoplasty in Osteoporotic Vertebral Fractures: A Retrospective Analysis

Yonghao Wu ORCID logo1ABCEF, Shuaiqi Zhu ORCID logo1ABCF, Yuqiao Li1ABDF, Chenfei Zhang ORCID logo1AEF, Weiwei Xia1ACFG, Zhenqi Zhu1DF, Kaifeng Wang1ADEG*

DOI: 10.12659/MSM.945884

Med Sci Monit 2024; 30:e945884

Table 1 Univariate analysis of BCD after percutaneous kyphoplasty for OVFs.

VariablesNon-displacement group (n=169)Displacement group (n=12)χ2/t value/ z valueP value
Sex0.0001.000#
 Male [n (%)]39 (23.1)3 (25.0)
 Female [n (%)]130 (76.9)9 (75.0)
Age (years)74.00 (66.00~80.50)77.00 (65.50~81.75)−0.160.873*
BMI (kg/m)24.10±3.4826.35±3.55−2.0780.039&
Underlying diseases
 Hypertension [n (%)]77 (45.6)6 (50.0)0.0890.766#
 Diabetes [n (%)]35 (20.7)1 (8.3)0.4400.507#
Cardiovascular and cerebrovascular diseases [n (%)]41 (24.3)5 (41.7)1.7910.181#
History of fracture at other sites1.3430.247#
 Yes [n (%)]29 (17.2)0 (0.0)
 No [n (%)]140 (82.8)12 (100.0)
Fractured vertebral segment0.2830.595#
 Thoracolumbar segment [n (%)]137 (81.1)11 (91.7)
 Nonthoracolumbar segment [n (%)]32 (18.9)1 (8.3)
Preoperative IVC4.1770.041#
 Yes [n (%)]114 (67.5)12 (100.0)
 No [n (%)]55 (32.5)0 (0.0)
Injected bone cement volume (ml)2.50 (2.50~3.00)2.75 (2.50~3.00)−1.0830.279*
Preoperative vertebral height (cm)1.55±0.421.65±0.300.4310.431&
Collapse rate of the vertebral body (%)23.98 (14.69~36.94)27.85 (20.08~34.94)−0.560.578*
Preoperative vertebral anterior margin height (cm)1.80±0.471.97±0.52−1.2550.211&
Postoperative vertebral anterior margin height (cm)1.98±0.472.35±0.54−2.6210.010&
Recovery rate of vertebral anterior margin height (%)4.90 (0.96~13.97)15.12 (7.39~21.97)−2.640.008*
Preoperative Cobb angle (°)13.30 (8.80~18.70)14.45 (6.88~21.65)−0.150.880*
Postoperative Cobb angle (°)12.00 (7.20~17.85)5.65 (2.45~16.33)−1.700.089*
Restoration rate of the Cobb angle (%)4.35 (1.82~14.14)32.50 (11.11~74.70)−3.140.002*
Volume of cement (ml)2.76±1.012.96±0.66−1.080.199&
Sagittal position of cement filling10.3330.006#
 1/3 of vertebral body [n (%)]12 (7.1)1 (8.3)
 2/3 of vertebral body [n (%)]52 (30.8)9 (75.0)
 Whole vertebral body [n (%)]105 (62.1)2 (16.7)
Contact between bone cement and endplate20.872<0.001#
 Non-cement-endplate-contact [n (%)]8 (4.7)4 (33.3)
 Contact with the upper vertebral endplates [n (%)]33 (19.5)5 (41.7)
 Contact with the lower vertebral endplates [n (%)]46 (27.2)3 (25.0)
 Contact with the upper and lower vertebral endplates [n (%)]82 (48.5)0 (0.0)
Distance between bone cement and vertebral endplates (cm)0.14 (0.00~0.43)0.43 (0.30~0.64)−3.150.002*
Bone cement distribution score7.00 (5.00~8.00)5.50 (4.00~6.00)−3.090.002*
Bone cement leakage22.056<0.001#
 Non-leakage [n (%)]121 (71.6)3 (25.0)
 Anterior leakage [n (%)]16 (9.5)6 (50.0)
 Posterior leakage [n (%)]7 (4.1)3 (25.0)
 Lateral leakage [n (%)]10 (5.9)0 (0.0)
 Disc leakage [n (%)]15 (8.9)0 (0.0)
Postoperative anti-osteoporosis treatment1.2520.263#
 Yes [n (%)]152 (89.9)9 (75.0)
 No [n (%)]17 (10.1)3 (25.0)
# value was obtained by chi-square test;
& value was obtained by independent samples test;
* value was obtained by Mann-Whitney U test.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750