Impact of Fresh Khat Extract on Proinflammatory Cytokines and Hepatic and Renal Responses

04 November 2024 : Animal Research

Siddig I. Abdelwahab^1ABCDEFG*, Manal M.E. Taha

^1ABCE, Sivakumar S. Sivagurunathan Moni

^2BC, Mahdi M. Alnajai

^3B, Ahmed A. Jerah^3BEG, Abdullah Farasani^4BEG, Saleh M. Abdullah^4BEG, Ieman A. Aljahdali^5BEG, Omar Oraibi

^6BEG, Bassem Oraibi^1BEG, Hassan A. Alfaifi^7BEG, Amal H. Alzahrani^8BEG, Yasir O.H. Babiker

^9BEG, Adel S. Al-Zubairi

^1011BE

DOI: 10.12659/MSM.946108

Med Sci Monit 2024; 30:e946108

Introduction Material and Methods Results Discussion Conclusions References

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Table 2 Glucose, hepatic markers and total bilirubin of female and male rats fed with the extract.

Groups	AST (U/L)		ALT (U/L)		ALP (U/L)		TBI (mg/Dl)
Groups	Male	Female	Male	Female	Male	Female	Male	Female
Control	336.33± 18.64	216.67± 29.84	109.67± 13.87	92.33± 10.79	227.00± 84.48	144.00± 30.0	0.17± 0.06	0.10± 0.01
100 mg/kg	270.33± 90.15	277.33± 36.96	110.33± 16.26	85.67± 21.94	265.33± 75.48	125.33± 22.01	0.13± 0.06	0.17± 0.06
300 mg/kg	270.67± 62.32	251.67± 33.65	92.67± 11.72	86.00± 3.46	171.33± 16.80	200.00± 60.36	0.17± 0.06	0.13± 0.06
500 mg/kg	267.33± 21.78	322.00± 26.89	98.00± 11.53	91.00± 7.21	213.00± 59.00	178.67± 23.63	0.17± 0.06	0.20± 0.01
The level of significance was set at

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