29 January 2025 : Database Analysis
Development and Validation of a Competitive Risk Model in Elderly Patients with Transitional Cell Bladder Carcinoma
Libin Yang
ABCDE 1, Chao Chen AC 1, Qianghui Wang AB 1, Zhiliang Zhuang EF 1, Tao Sun EF 1*
DOI: 10.12659/MSM.946332
Med Sci Monit 2025; 31:e946332
Table 1 Clinical baseline characteristics of elderly individuals diagnosed with tcBC.
| Training (N=42905) | Validation (N=18388) | ALL (N=61293) | P | |
|---|---|---|---|---|
| Age | 74.96±8.54 | 74.86±8.50 | 74.93±8.52 | 0.176 |
| Sex | 0.948 | |||
| Female | 9794 (22.8%) | 4193 (22.8%) | 13987 (22.8%) | |
| Male | 33111 (77.2%) | 14195 (77.2%) | 47306 (77.2%) | |
| Race | 0.855 | |||
| White | 38324 (89.3%) | 16446 (89.4%) | 54770 (89.4%) | |
| Black | 2100 (4.9%) | 929 (5.1%) | 3029 (4.9%) | |
| Others | 2481 (5.8%) | 1013 (5.5%) | 3494 (5.7%) | |
| Marital status | 0.165 | |||
| Married | 24872 (58.0%) | 10775 (58.6%) | 35647 (58.2%) | |
| Unmarried | 14023 (32.7%) | 5916 (32.2%) | 19939 (32.5%) | |
| Unknown | 4010 (9.3%) | 1697 (9.2%) | 5707 (9.3%) | |
| T | 0.757 | |||
| Ta/Tis/T1 | 35095 (81.8%) | 15066 (81.9%) | 50161 (81.8%) | |
| T2 | 5805 (13.5%) | 2440 (13.3%) | 8245 (13.5%) | |
| T3 | 1041 (2.4%) | 448 (2.4%) | 1489 (2.4%) | |
| T4 | 964 (2.2%) | 434 (2.4%) | 1398 (2.3%) | |
| N | 0.128 | |||
| N0 | 41808 (97.4%) | 17858 (97.1%) | 59666 (97.3%) | |
| N1 | 406 (0.9%) | 205 (1.1%) | 611 (1.0%) | |
| N2 | 522 (1.2%) | 262 (1.4%) | 784 (1.3%) | |
| N3 | 169 (0.4%) | 63 (0.3%) | 232 (0.4%) | |
| M | 0.241 | |||
| M0 | 42001 (97.9%) | 17973 (97.7%) | 59974 (97.8%) | |
| M1 | 904 (2.1%) | 415 (2.3%) | 1319 (2.2%) | |
| Grade | 0.146 | |||
| I–II | 13266 (30.9%) | 5586 (30.4%) | 18852 (30.8%) | |
| III–IV | 20032 (46.7%) | 8614 (46.8%) | 28646 (46.7%) | |
| Surgery | 0.108 | |||
| Unknown | 9607 (22.4%) | 4188 (22.8%) | 13795 (22.5%) | |
| TURBT | 37888 (88.3%) | 16195 (88.1%) | 54083 (88.2%) | |
| P/R | 2458 (5.7%) | 1062 (5.8%) | 3520 (5.7%) | |
| No surgery | 2559 (6.0%) | 1131 (6.2%) | 3690 (6.1%) | |
| Chemotherapy | 0.089 | |||
| No/unknown | 32719 (76.3%) | 13905 (75.6%) | 46624 (76.1%) | |
| Yes | 10186 (23.7%) | 4483 (24.4%) | 14669 (23.9%) | |
| Radiation | 0.65 | |||
| No/unknown | 40865 (95.2%) | 17498 (95.2%) | 58363 (95.2%) | |
| Yes | 2040 (4.8%) | 890 (4.8) | 2930 (4.8%) | |
| Brain | 0.239 | |||
| No | 42885 (99.9%) | 18375 (99.9%) | 61260 (99.9%) | |
| Yes | 20 (0.1%) | 13 (0.1%) | 33 (0.1%) | |
| Bone | 0.407 | |||
| No | 42569 (99.2%) | 18232 (99.2%) | 60801 (99.2%) | |
| Yes | 336 (0.8%) | 156 (0.8%) | 492 (0.8) | |
| Liver | 0.635 | |||
| No | 42740 (99.6%) | 18322 (99.6%) | 61062 (99.6%) | |
| Yes | 165 (0.4%) | 66 (0.4%) | 231 (0.4) | |
| Lung | 0.431 | |||
| No | 42608 (99.3%) | 18250 (99.2%) | 60858 (99.3%) | |
| Yes | 297 (0.7%) | 138 (0.8%) | 435 (0.7%) | |
| Survival (months) | 63.45±37.20 | 62.61±37.35 | 62.50±37.25 | 0.569 |
| TURBT – transurethral resection of bladder tumor; P/R – partial/radical cystectomy. | ||||