25 November 2024 : Clinical Research
Efficacy and Safety of Direct Oral Anticoagulants After Mechanical Thrombectomy in Venous Thromboembolism: A Comparative Study of 55 Patients
Wei-Chieh Lee123ABCDEF*, Chon-Seng Hong2BD, Wei-Ting Chang12EF, Chia-Te Liao4F, Po-Sen Huang4B, Shen-Chung Huang4B, Chih-Hsien Lin4B, Chun-Yen Chiang4B, Zhih-Cherng Chen
4F, Jhih-Yuan Shih43DF
DOI: 10.12659/MSM.946362
Med Sci Monit 2024; 30:e946362
Table 1 Baseline characteristics of the study patients.
| Group 1 (n=14) | Group 2 (n=41) | P value | |
|---|---|---|---|
| PE | 6 (42.9) | 22 (53.7) | 0.547 |
| DVT | 11 (78.6) | 27 (65.9) | 0.510 |
| Bilateral site | 1 (7.1) | 2 (4.9) | 0.757 |
| Right site | 5 (35.7) | 9 (22.0) | 0.314 |
| Left site | 5 (35.7) | 16 (39.0) | 0.828 |
| PE and DVT | 3 (21.4) | 8 (19.5) | 0.877 |
| Age (years) | 55±19.9 | 59±18.8 | 0.457 |
| Male sex (%) | 8 (57.1) | 15 (36.6) | 0.183 |
| BMI (kg/m) | 25.9±5.0 | 26.1±4.5 | 0.883 |
| 11.4±7.5 | 15.6±6.8 | 0.565 | |
| Smoking (%) | 2 (14.3) | 8 (19.5) | 0.662 |
| Hypertension (%) | 6 (42.9) | 21 (51.2) | 0.758 |
| Diabetes mellitus (%) | 3 (21.4) | 10 (24.4) | 0.822 |
| Dyslipidemia (%) | 3 (21.4) | 7 (17.1) | 0.703 |
| Prior stroke (%) | 1 (7.1) | 6 (14.6) | 0.664 |
| Coronary artery disease (%) | 2 (14.3) | 2 (4.9) | 0.265 |
| Heart failure (%) | 1 (7.1) | 1 (2.4) | 0.448 |
| Chronic kidney disease (%) | 2 (14.3) | 3 (7.3) | 0.592 |
| Atrial fibrillation (%) | 1 (7.1) | 0 (0) | 0.255 |
| Creatinine (mg/dL) | 0.95±0.28 | 0.87±0.26 | 0.340 |
| Warfarin (%) | 0 (0) | 0 (0) | – |
| Dabigatran (%) | 3 (21.4) | 10 (24.4) | 0.822 |
| Rivaroxaban (%) | 6 (42.9) | 18 (43.9) | 0.946 |
| Apixaban (%) | 4 (28.6) | 12 (29.3) | 0.960 |
| Edoxaban (%) | 2 (14.3) | 9 (22.0) | 0.709 |
| Change different OAC (%) | 1 (7.1) | 8 (19.5) | 0.283 |
| Data are expressed as mean ± standard deviation or as number (percentage). PE – pulmonary embolism; DVT – deep vein thrombosis; BMI – body mass index; OAC – oral anticoagulation. | |||