Efficacy and Safety of Direct Oral Anticoagulants After Mechanical Thrombectomy in Venous Thromboembolism: A Comparative Study of 55 Patients

Wei-Chieh Lee; Chon-Seng Hong; Wei-Ting Chang; Chia-Te Liao; Po-Sen Huang; Shen-Chung Huang; Chih-Hsien Lin; Chun-Yen Chiang; Zhih-Cherng Chen; Jhih-Yuan Shih

doi:10.12659/MSM.946362

25 November 2024 : Clinical Research

Efficacy and Safety of Direct Oral Anticoagulants After Mechanical Thrombectomy in Venous Thromboembolism: A Comparative Study of 55 Patients

Wei-Chieh Lee^123ABCDEF*, Chon-Seng Hong^2BD, Wei-Ting Chang^12EF, Chia-Te Liao^4F, Po-Sen Huang^4B, Shen-Chung Huang^4B, Chih-Hsien Lin^4B, Chun-Yen Chiang^4B, Zhih-Cherng Chen

^4F, Jhih-Yuan Shih^43DF

DOI: 10.12659/MSM.946362

Med Sci Monit 2024; 30:e946362

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Table 3 Clinical presentation and medication use in patients with thrombophilia.

Patient number	Patient demographics				Thrombophilia type and use of OAC
Patient number	Sex	Age (years)	BMI (kg/m2)	Cr (mg/dL)	Thrombophilia	Index event	Drug	Months after OAC
1	Male	75	15.6	0.58	Thrombin III	Right iliofemoral vein	Rivaroxaban	11
2	Female	43	31.8	0.79	Protein S	Left iliofemoral vein	Apixaban	23
3	Female	39	28.7	0.66	Protein S	Bilateral pulmonary trunk embolism	Dabigatran	6
4	Male	23	27.3	1.05	Protein C	Left iliofemoral vein	Rivaroxaban	20
5	Male	74	26.2	1.32	Thrombin III	Bilateral pulmonary trunk embolism and Right iliofemoral vein	Rivaroxaban	18
6	Female	80	17.4	0.74	Thrombin III	Left iliofemoral vein	Rivaroxaban	19
7	Male	71	25.4	1.5	Protein S	Right ilio-femoral vein	Rivaroxaban	7
8	Male	34	25.6	0.73	Thrombin III	Bilateral pulmonary trunk embolism	Edoxaban	5
9	Male	61	30.6	1.3	Thrombin III	Right iliofemoral vein	Edoxaban→ Dabigatran	2
10	Male	48	18.8	0.84	Protein C	Bilateral pulmonary trunk embolism	Apixaban	3
11	Female	52	28.3	1.2	Thrombin III	Bilateral pulmonary trunk embolism and left iliofemoral vein	Apixaban	1
12	Female	53	27.3	0.94	Protein S	Bilateral pulmonary trunk embolism and left iliofemoral vein	Apixaban	13
13	Female	83	28.8	0.89	Protein S	Bilateral iliofemoral vein	Rivaroxaban	19
14	Female	27	30.2	0.72	Protein S	Right iliofemoral vein	Dabigatran	12
BMI – body mass index; Cr – creatinine; OAC – oral anticoagulation.

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Efficacy and Safety of Direct Oral Anticoagulants After Mechanical Thrombectomy in Venous Thromboembolism: A Comparative Study of 55 Patients

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