14 May 2025 : Clinical Research
Efficacy of Prolotherapy for Temporomandibular Joint Dysfunction: An Interventional Clinical Study
Khalil Assiri
AG 1, Abdullah Alqarni AF 1, Hussain Almubarak DF 1, Sultan Mohammed Kaleem ABEF 1*, Saeed Alassiri BCE 1, Fawaz Abdul Hamid Baig ABF 2, Ajmal Muhammed BD 1, Mohammad Zahir Kota BF 2, Ali Azhar Dawasaz BE 1, Ali Mosfer Alqahtani CD 1, Hassan Ahmed Assiri CD 1, Saeed Abdullah Arem DF 1, Salma Abubaker Abbas Ali CF 1, Master Luqman Mannakandath DF 1
DOI: 10.12659/MSM.946650
Med Sci Monit 2025; 31:e946650
Table 6 Efficacy of prolotherapy for chronic temporomandibular disorders.
| Prolotherapy variables | VAS pain score (0–10) | Average mouth opening in terms N=35 mm (32–77 mm) | COR |
|---|---|---|---|
| Before treatment | 7 | 30 | 0.11 |
| First month | 7 | 32.3 | 1.41 |
| Third month | 4.42 | 36.73 | 2 |
| Sixth month | 1.85 | 39.57 | 5.2 |
| Mean | 4.068 | 27.38 | 2.18 |
| 95% CI | 0.2–7.9 | 7.6–47.1 | 1.26–5.6 |
| P-value | 0.07 | 0.04 | |
| CI – confidence interval; COR – Crude’s odds ratio. | |||