28 December 2024 : Database Analysis
Liver Cirrhosis as a Predictor of Infection Risk in Patients Undergoing Ventriculoperitoneal Shunt Surgery: A Retrospective Cohort Analysis from the Taiwan National Health Insurance Research Database (NHIRD)
Yu-Chung Juan ADEF 1,2, Hung-Lin Lin ADF 1, Yu-hsiang Lin
ADF 1, Wen-Miin Liang ACDG 3, Yu-Kai Cheng DF 1,4, Yu-Jun Chang DE 5, Chien-Tung Yang DF 1, Der-Yang Cho DF 1, Chun-Chung Chen ADEF 1,2,6*
DOI: 10.12659/MSM.946745
Med Sci Monit 2024; 30:e946745
Table 2 Prediction for occurrence of infection at 6 months.
| Crude | Adjusted | |||
|---|---|---|---|---|
| sHR | P-value | sHR | P-value | |
| Liver cirrhosis | 1.35 (1.05–1.73) | 0.018 | 1.41 (1.10–1.81) | 0.007 |
| Age | 0.98 (0.98–0.99) | <0.001 | 0.99 (0.98–0.99) | <0.001 |
| Male vs Female | 1.33 (1.18–1.50) | <0.001 | 1.25 (1.10–1.41) | 0.001 |
| Steroid use | 1.40 (1.10–1.78) | 0.006 | 1.56 (1.22–2.00) | <0.001 |
| EVD | 1.13 (0.98–1.30) | 0.099 | 1.03 (0.89–1.19) | 0.709 |
| Surgery history | ||||
| Cerebral hemorrhage | 1.61 (1.33–1.94) | <0.001 | 1.48 (1.19–1.83) | <0.001 |
| Aneurysm | 1.29 (0.88–1.89) | 0.186 | 1.32 (0.90–1.95) | 0.157 |
| Brain tumor | 1.22 (0.89–1.68) | 0.224 | 1.14 (0.82–1.59) | 0.433 |
| Decompressive craniectomy | 1.70 (1.34–2.15) | <0.001 | 1.37 (1.06–1.78) | 0.018 |
| Cranioplasty | 1.31 (0.97–1.77) | 0.076 | 0.92 (0.66–1.29) | 0.643 |
| Surgery (same hospitalization) | ||||
| Cerebral hemorrhage | 1.54 (1.34–1.77) | <0.001 | 1.40 (1.20–1.63) | <0.001 |
| Aneurysm | 0.97 (0.78–1.21) | 0.767 | 1.02 (0.81–1.28) | 0.888 |
| Brain tumor | 1.31 (0.96–1.78) | 0.093 | 1.19 (0.86–1.63) | 0.298 |
| Decompressive craniectomy | 1.63 (1.34–1.99) | <0.001 | 1.31 (1.06–1.61) | 0.012 |
| Cranioplasty | 1.94 (1.66–2.28) | <0.001 | 1.34 (1.11–1.61) | 0.002 |
| Comorbidities | ||||
| Diabetes | 0.87 (0.77–0.99) | 0.033 | 1.04 (0.91–1.19) | 0.577 |
| Hypertension | 0.78 (0.69–0.87) | <0.001 | 0.96 (0.84–1.09) | 0.518 |
| Congestive heart failure | 0.67 (0.52–0.88) | 0.004 | 0.80 (0.61–1.05) | 0.108 |
| ESRD | 0.77 (0.61–0.98) | 0.033 | 0.92 (0.72–1.18) | 0.528 |
| Malnutrition | 1.15 (0.48–2.76) | 0.762 | 1.25 (0.52–3.01) | 0.621 |
| Pneumonia | 1.00 (0.87–1.15) | >0.999 | 0.98 (0.85–1.12) | 0.725 |
| UTI | 0.81 (0.71–0.93) | 0.002 | 0.92 (0.80–1.06) | 0.243 |
| sHR – subdistribution hazard ratio; EVD – external ventricular drainage; ESRD – end-stage renal disease; UTI – urinary tract infections. | ||||