28 December 2024 : Database Analysis
Liver Cirrhosis as a Predictor of Infection Risk in Patients Undergoing Ventriculoperitoneal Shunt Surgery: A Retrospective Cohort Analysis from the Taiwan National Health Insurance Research Database (NHIRD)
Yu-Chung Juan ADEF 1,2, Hung-Lin Lin ADF 1, Yu-hsiang Lin
ADF 1, Wen-Miin Liang ACDG 3, Yu-Kai Cheng DF 1,4, Yu-Jun Chang DE 5, Chien-Tung Yang DF 1, Der-Yang Cho DF 1, Chun-Chung Chen ADEF 1,2,6*
DOI: 10.12659/MSM.946745
Med Sci Monit 2024; 30:e946745
Table 3 Prediction for occurrence of infection at 1 year.
| Crude | Adjusted | |||
|---|---|---|---|---|
| sHR | P-value | sHR | P-value | |
| Liver cirrhosis | 1.33 (1.07–1.66) | 0.009 | 1.39 (1.12–1.73) | 0.003 |
| Age | 0.98 (0.98–0.99) | <0.001 | 0.99 (0.98–0.99) | <0.001 |
| Male vs Female | 1.28 (1.15–1.42) | <0.001 | 1.21 (1.08–1.34) | 0.001 |
| Steroid use | 1.30 (1.05–1.62) | 0.019 | 1.42 (1.13–1.78) | 0.002 |
| EVD | 1.20 (1.07–1.35) | 0.003 | 1.09 (0.96–1.24) | 0.169 |
| Treat history | ||||
| Cerebral hemorrhage | 1.55 (1.32–1.83) | <0.001 | 1.38 (1.14–1.66) | 0.001 |
| Aneurysm | 1.26 (0.90–1.75) | 0.172 | 1.28 (0.92–1.80) | 0.143 |
| Brain tumor | 1.32 (1.00–1.73) | 0.050 | 1.28 (0.96–1.70) | 0.090 |
| Decompressive craniectomy | 1.72 (1.41–2.11) | <0.001 | 1.36 (1.09–1.71) | 0.007 |
| Cranioplasty | 1.43 (1.11–1.83) | 0.005 | 1.05 (0.80–1.40) | 0.708 |
| Treat (same hospitalization) | ||||
| Cerebral hemorrhage | 1.55 (1.37–1.74) | <0.001 | 1.36 (1.19–1.55) | <0.001 |
| Aneurysm | 1.05 (0.87–1.26) | 0.609 | 1.08 (0.90–1.31) | 0.413 |
| Brain tumor | 1.35 (1.03–1.76) | 0.032 | 1.21 (0.91–1.60) | 0.183 |
| Decompressive craniectomy | 1.77 (1.50–2.08) | <0.001 | 1.38 (1.16–1.65) | <0.001 |
| Cranioplasty | 2.03 (1.77–2.32) | <0.001 | 1.40 (1.20–1.64) | <0.001 |
| Comorbidities | ||||
| Diabetes | 0.85 (0.76–0.96) | 0.006 | 1.02 (0.90–1.15) | 0.783 |
| Hypertension | 0.76 (0.69–0.84) | <0.001 | 0.92 (0.82–1.03) | 0.161 |
| Congestive heart failure | 0.71 (0.57–0.89) | 0.003 | 0.82 (0.65–1.03) | 0.091 |
| ESRD | 0.84 (0.69–1.03) | 0.098 | 1.02 (0.83–1.25) | 0.868 |
| Malnutrition | 1.22 (0.58–2.57) | 0.593 | 1.31 (0.62–2.75) | 0.481 |
| Pneumonia | 1.11 (0.99–1.24) | 0.078 | 1.08 (0.96–1.21) | 0.209 |
| UTI | 0.87 (0.78–0.97) | 0.016 | 0.98 (0.87–1.10) | 0.707 |
| sHR – subdistribution hazard ratio; EVD – external ventricular drainage; ESRD – end-stage renal disease; UTI – urinary tract infections. | ||||