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28 December 2024 : Database Analysis  

Liver Cirrhosis as a Predictor of Infection Risk in Patients Undergoing Ventriculoperitoneal Shunt Surgery: A Retrospective Cohort Analysis from the Taiwan National Health Insurance Research Database (NHIRD)

Yu-Chung Juan ADEF 1,2, Hung-Lin Lin ADF 1, Yu-hsiang Lin ORCID logo ADF 1, Wen-Miin Liang ACDG 3, Yu-Kai Cheng DF 1,4, Yu-Jun Chang DE 5, Chien-Tung Yang DF 1, Der-Yang Cho DF 1, Chun-Chung Chen ADEF 1,2,6*

DOI: 10.12659/MSM.946745

Med Sci Monit 2024; 30:e946745

Table 5 Use of the 1: 10 matching method and the Fine and Gray regression hazards model to predict the occurrence of infections within 1 year.

CrudeAdjusted
sHRP-valuesHRP-value
Liver cirrhosis1.44 (1.15–1.81)0.0021.42 (1.13–1.78)0.003
Age0.98 (0.98–0.99)<0.0010.99 (0.98–1.00)0.001
Male vs Female1.38 (1.18–1.62)<0.0011.25 (1.06–1.47)0.009
Steroid use1.35 (0.98–1.86)0.0651.45 (1.05–2.01)0.024
EVD1.31 (1.10–1.57)0.0021.24 (1.03–1.49)0.026
Treat history
 Cerebral hemorrhage1.72 (1.35–2.18)<0.0011.65 (1.25–2.17)<0.001
 Aneurysm1.29 (0.77–2.15)0.3291.29 (0.77–2.17)0.331
 Brain tumor1.10 (0.70–1.74)0.6741.04 (0.65–1.67)0.871
 Decompressive craniectomy1.29 (0.91–1.85)0.1541.07 (0.73–1.57)0.739
 Cranioplasty1.59 (1.10–2.31)0.0151.14 (0.74–1.74)0.550
Treat (same hospitalization)
 Cerebral hemorrhage1.39 (1.16–1.68)<0.0011.23 (1.00–1.51)0.045
 Aneurysm0.95 (0.70–1.28)0.7280.96 (0.71–1.31)0.811
 Brain tumor1.43 (0.93–2.19)0.0991.29 (0.83–1.99)0.254
 Decompressive craniectomy1.54 (1.18–2.01)0.0011.31 (0.99–1.74)0.057
 Cranioplasty1.59 (1.26–2.00)<0.0011.17 (0.90–1.51)0.237
Comorbidities
 Diabetes0.84 (0.71–0.98)0.0290.95 (0.80–1.12)0.515
 Hypertension0.73 (0.63–0.85)<0.0010.83 (0.71–0.98)0.027
 Congestive heart failure0.71 (0.52–0.97)0.0310.80 (0.58–1.10)0.166
 ESRD0.95 (0.73–1.24)0.7161.13 (0.85–1.49)0.402
 Malnutrition1.08 (0.35–3.36)0.8921.08 (0.35–3.37)0.890
 Pneumonia1.04 (0.88–1.24)0.6151.00 (0.84–1.19)0.995
 UTI0.85 (0.72–1.00)0.0510.95 (0.80–1.13)0.557
sHR – subdistribution hazard ratio; EVD – external ventricular drainage; ESRD – end-stage renal disease; UTI – urinary tract infections.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750