NSTEMI Risk Prediction with the Combination of the Biomarkers Epicardial Adipose Tissue and Soluble Suppression of Tumorigenicity 2

10 March 2025 : Clinical Research

Jiayu Yin^1ACEFG, Bowen Qiu^2BCEF, Tingting Li^1CE, Yifei Tao^3ADE*, Xiaosong Gu^1AG

DOI: 10.12659/MSM.947019

Med Sci Monit 2025; 31:e947019

Introduction Material and Methods Results Discussion Conclusions References

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Table 4 Incremental Value of sST2 and EATi in the Prediction of MACEs.

	NRI		IDI
	Estimate (95% CI)	P	Estimate (95% CI)	P
Model a: age+LVEF	Reference	–	Reference	–
Model b: age+LVEF+High sST2	0.2083 (0.040–0.377)	0.015	0.0490 (0.025–0.073)	<0.001
Model c: age+LVEF+High EATi	0.2638 (0.090–0.438)	0.003	0.0683 (0.040–0.097)	<0.001
Model d: age+LVEF+High sST2+High EATi	0.4071 (0.231–0.583)	<0.001	0.1356 (0.091–0.180)	<0.001
MACEs – major adverse cardiac events; LVEF – left ventricular ejection fraction; sST2 – soluble suppression of tumorigenicity 2; EATi – epicardial adipose tissue index; CI – confidence interval; IDI – integrated discrimination index; NRI – net reclassification improvement.

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