11 May 2025 : Clinical Research
Impact of Dexmedetomidine on Analgesia and Inflammatory Response in Knee Surgery: A Study of IPACK and ACB Techniques
Jian Zeng
ABCDEFG 1, Li Zhao ABCDEF 2, Jinpei Xue ACDFG 1, Zhijun Yao CDEF 1, Xiongtiao Yang ACDF 1, Xiao Zhong BCD 1, Yulong Fu ABF 1, Jianpeng Li ABD 1, Yang Cui AB 1, Zhiqin Chen AB 1, Jiamin Zhong A 1, Hongyi Lei ACDEFG 1*
DOI: 10.12659/MSM.947087
Med Sci Monit 2025; 31:e947087
Table 6 Maximum postoperative walking distance.
| Standard error | Mean difference (95% CI) | P value | |
|---|---|---|---|
| 24 hours after surgery | |||
| Group E vs C | 1.93 | 11.16 (6.44 to 15.88) | <0.001 |
| Group I vs C | 1.95 | 4.48 (−0.28 to 9.22) | =0.072 |
| 48 hours after surgery | |||
| Group E vs C | 5.34 | 30.53 (17.52 to 43.54) | <0.001 |
| Group I vs C | 5.38 | 14.14 (1.03 to 27.24) | =0.03 |
| Use the single-factor ANOVA followed by Bonferroni correction for multiple tests. 95% CI, 95% confidence interval. The value is the comparison between groups. Group E vs C, Group E was compared with Group C. Group I vs C, Group I was compared with Group C. Group E, perineural DEX adjuvant+IPACK+ACB. Group I, intravenous DEX+IPACK+ACB. Group C, (IPACK+ACB) control group. | |||