29 May 2025 : Clinical Research
Pentraxin 3 as a Prognostic Biomarker in Aneurysmal Subarachnoid Hemorrhage
Dong-Liang Wang ABCD 1, Feng Jiao BCDE 1, Yi-Lin Jiang ABC 1, Hai-Dong Song ABC 1, Bin Li BCD 2, Qun Gao BD 2, Bin Wang DF 2, Bo Hei CDF 2, Jing-Ru Zhou AF 2*DOI: 10.12659/MSM.947133
Med Sci Monit 2025; 31:e947133
Table 3 Efficacy of various indicators for assessing poor prognosis.
| Indicators | Threshold value | Sensitivity (%) | Specificity (%) | Youden Index | AUC | 95% CI |
|---|---|---|---|---|---|---|
| PTX3 (ng/ml) | 1.990 | 70.0 | 78.0 | 0.480 | 0.790 | 0.676–0.890 |
| Hunt-Hess (score) | 2.43 | 78.5 | 75.0 | 0.535 | 0.785 | 0.675–0.900 |
| WFNS (score) | 2.37 | 79.5 | 81.0 | 0.605 | 0.830 | 0.735–0.930 |
| mFisher (score) | 2.39 | 73.5 | 66.5 | 0.400 | 0.775 | 0.670–0.880 |
| PTX3 – pentraxin 3; WFNS – World Federation of Neurosurgical Societies; mFisher – modified Fisher grading scale; AUC – area under the curve; CI – confidence interval. | ||||||