09 June 2025 : Clinical Research
Self-Management-Centric Cardiac Rehabilitation for Acute Coronary Syndrome Patients During the COVID-19 Pandemic
Yiwen Wang ABCE 1, Haowen Shi BCEF 1, Min Zhang BDF 1, Yang Duan D 1, Zhi Li BDF 1, Lei Chen BCD 1, Yixuan Wu BCF 1, Yanfei Ren BF 1, Yuan Lu ADEG 1*DOI: 10.12659/MSM.947235
Med Sci Monit 2025; 31:e947235
Table 4 Cox regression investigating the factors predicting MACEs.
| Covariates | Crude HR (95% CI) | P | Adjusted HR (95% CI) | P |
|---|---|---|---|---|
| SMCCR (finished vs not finished) | 0.43 (0.30–0.60) | <0.001 | 0.42 (0.3–0.59) | |
| Diagnosis (STEMI vs NSTEACS) | 0.6 (0.44–0.82) | 0.001 | 0.59 (0.43–0.82) | |
| Age ≤44ys | Ref. | |||
| 45–64ys | 3.04 (0.95–9.70) | 0.061 | 3.32 (1.03–10.70) | |
| ≥65ys | 4.66 (1.48–14.69) | 0.009 | 3.72 (1.15–11.99) | |
| SBP (≥130/80 vs <130/80 mmHg | 0.83 (0.61–1.10) | 0.25 | ||
| HR | 1.2 (1–1.4) | 0.013 | 1.09 (0.93–1.28) | 0.269 |
| LVEDD (>50 vs ≤50 mm) | 1.4 (1–1.9) | 0.0241 | 1.1 (0.79–1.55) | 0.561 |
| KILLIP (>I vs I) | 3.2 (2.3–4.5) | <0.001 | 1.74 (1.16–2.62) | |
| HLOS (>5 vs ≤5d) | 2 (1.5–2.7) | <0.001 | 1.53 (1.08–2.16) | |
| BB (Yes vs No) | 0.56 (0.34–0.83) | 0.009 | 0.53 (0.33–0.83) | |
| HbA1c | 1.1 (0.96–1.3) | 0.151 | ||
| EH (Yes vs No) | 1.5 (1.1–2) | 0.015 | 1.49 (1.09–2.05) | |
| NT-proBNP | 1.4 (1.3–1.5) | <0.001 | 1.13 (0.98–1.31) | 0.094 |
| eGFR | 0.7 (0.61–0.8) | <0.001 | 0.96 (0.79–1.16) | 0.638 |
| hsTnT | 1.1 (0.99–1.3) | 0.075 | ||
| CKMB | 1.1 (0.93–1.3) | 0.28 | ||
| LVEF category | ||||
| LVEF ≤40% | Ref. | |||
| LVEF 41–49% | 0.53 (0.33–0.85) | 0.009 | 0.59 (0.36–0.97) | 0.037 |
| LVEF ≥50% | 0.24 (0.16–0.37) | <0.001 | 0.47 (0.27–0.79) | |
| Urgency of PCI | ||||
| No PCI | Ref. | |||
| Emergency PCI | 1.19 (0.70–2.04) | 0.519 | 0.73 (0.45–1.18) | 0.199 |
| Urgent PCI | 2.41 (1.34–4.35) | 0.003 | 0.91 (0.48–1.73) | 0.777 |
| Elective PCI | 1.07 (0.58–1.97) | 0.827 | 0.68 (0.39–1.19) | 0.176 |