Associations Between Dopamine Beta-Hydroxylase Gene Polymorphisms and Restless Legs Syndrome: A Case-Control Study

23 August 2025 : Clinical Research

Fatma Ebru Algül

^{ACEF 1*}, Sinan Tatli

^{BDE 2}, Elif Yesilada

^{ADE 3}

DOI: 10.12659/MSM.947267

Med Sci Monit 2025; 31:e947267

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Table 2 Hardy-Weinberg equilibrium test results for rs129882, rs732833, and rs1611115 polymorphisms.

Polymorphism	Genotype	n (%)	p-Value
RS129882	CC	114 (56)	0.941^a
	CT	75 (37)
	TT	14 (7)
RS732833	CC	82 (40)	0.931^a
	CT	96 (47)
	TT	25 (12)
RS1611114	CC	115 (57)	0.904^a
	CT	74 (36)
	TT	14 (7)
^a Pearson chi-square test, p>0.05 suggests that the population is in Hardy-Weinberg equilibrium for the respective polymorphism.

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