Evaluation of Inflammatory Biomarkers in Parotid Tumors

17 August 2025 : Clinical Research

Aykut Ikinciogullari

^{ABCDEF 1*}, Burak Hazir

^{ABCDEF 1}, Erdem Aggunlu

^{ABCDEF 1}, Mustafa Colak

^{ACDEF 1}, Serdar Ensari

^{ADEF 1}, Haci Huseyin Dere

^{ADEF 1}

DOI: 10.12659/MSM.947334

Med Sci Monit 2025; 31:e947334

Authors information Article notes Copyright and License information

Introduction Material and Methods Results Discussion Conclusions References

Related articles Order reprints Share article Share by email

View HTML version

Table 6 Diagnostic performance of NLR, PLR, SII, and SIRI in differentiating Warthin tumors from pleomorphic adenomas.

	AUC	Sensitivity	Specificity	PPV	NPV	Accuracy	Cut-Off
NLR	0.59	0.66	0.54	0.48	0.71	0.58	2
PLR	0.61	0.45	0.81	0.61	0.70	0.67	93.4
SII	0.53	0.31	0.80	0.50	0.64	0.61	690
SIRI	0.71	0.82	0.61	0.57	0.84	0.69	0.85
AUC – area under the curve; PPV – positive predictive value; NPV – negative predictive value; NLR – neutrophil to lymphocyte ratio; PLR – platelet-to-lymphocyte ratio; SII – systemic immune inflammation index; SIRI – systemic inflammation response index.

Back to the Article