12 March 2025 : Clinical Research
Comparative Analysis of 5 cmH₂O Versus 10 cmH₂O PEEP on Cerebral Oxygen Saturation in Brain Tumor Surgery: A Randomized Controlled Clinical Study
Halide Hande Şahinkaya
ABCDEFG 1, Alper Tabanli ACEG 2*, Gulsen Ozgenc ADFG 3, Caglar Ayar CDFG 4, Cafer Ak DEFG 5, Gozde Gursoy Cirkinoglu BCEF 4, Sermin Altunbas CDEF 4, Zeki Tuncel Tekgül ABEF 4
DOI: 10.12659/MSM.947379
Med Sci Monit 2025; 31:e947379
Table 1 Demographic and clinical characteristics of patients.
| Parameter | Group I (n=31) | Group II (n=33) | P value |
|---|---|---|---|
| Age (years) | 61 (11) | 60 (35) | 0.400 |
| Sex (M/F) | 12 (19.7)/19 (61.3) | 15 (45.5)/18 (54.5) | 0.314 |
| Height (cm) | 167 (5) | 168 (12) | 0.588 |
| Weight (kg) | 70 (12) | 79 (21) | 0.120 |
| Comorbidities (n) | 0.169 | ||
| None | 9 (29) | 16 (48.5) | |
| HT | 16 (51.6) | 14 (42.3) | |
| DM | 3 (9.7) | 3 (9.1) | |
| CAD | 3 (9.7) | 0 | |
| ASA (n) | 0.103 | ||
| I | 3 (9.7) | 10 (30.3) | |
| II | 12 (38.7) | 8 (24.2) | |
| III | 16 (51.6) | 15 (45.5) | |
| Smoking (yes/no) | 16 (51.6)/15 (48.4) | 9 (27.3)/24 (72.7) | 0.072 |
| Preoperative Hg (mg/dL) | 13.02±2.21 | 13.16±1.85 | 0.793 |
| Preoperative Htc (%) | 38 (3.4) | 39.7 (3.8) | 0.861 |
| Data are presented as median (IQR) and n (%). F – Female; M – Male; ASA – American Society of Anesthesiologists Physical Status Classification System; BMI – body mass index; HT – hypertension; DM – diabetes mellitus; CAD – coronary artery disease; Hg – hemoglobin; Htc – hematocrit. | |||