28 May 2025 : Clinical Research
Effect of Prophylactic Intraoperative Tranexamic Acid on Postpartum Blood Loss Following Cesarean Section at a Single Center
Abarham Martadiansyah
ABE 1*, Nuswil Bernolian ABE 1, Putri Mirani E 1, Peby Maulina Lestari E 1, Irfannuddin Irfannuddin ACE 2, Nia Savitri Tamzil DF 2, Asoly Giovano Imartha ABCDEF 3, Muhammad Al Farisi Sutrisno CDEF 3, Widya Audisti E 3, Bella Stevanny CDEF 3
DOI: 10.12659/MSM.947904
Med Sci Monit 2025; 31:e947904
Table 2 Hemorrhage characteristics.
| Amount of blood/fluid | Group | Subjects (N=88) | P value | |
|---|---|---|---|---|
| Intervention (n=44) | Intervention (n=44) | |||
| Underpad | ||||
| Mean±SD | 226.1±91.7 | 254.1±116.0 | 240.1±104.9 | 0.264a |
| Median | 220 | 260 | 260 | |
| Min–Max | 90–440 | 90–440 | 90–440 | |
| Suction | ||||
| Mean±SD | 693.2±295.2 | 814.8±250.9 | 753.9±279.2 | 0.044* |
| Median | 725 | 800 | 750 | |
| Min–Max | 150–1700 | 350–1500 | 150–1700 | |
| Gauze | ||||
| Mean±SD | 174.3±68.0 | 205.7±67.7 | 190.0±69.3 | 0.014* |
| Median | 160 | 200 | 180 | |
| Min–Max | 85–470 | 80–360 | 80–470 | |
| Amount of liquid underpad + suction + gauze | ||||
| Mean±SD | 1193.9±694.9 | 1274.5±330.4 | 1234.2±542.5 | 0.022* |
| Median | 1060 | 1245 | 1165 | |
| Min–Max | 615–5115 | 600–1995 | 600–5115 | |
| Amniotic volume (ml) | ||||
| Mean±SD | 406.0±206.9 | 422.4±180.5 | 414.2±193.2 | 0.382a |
| Median | 350 | 400 | 390 | |
| Min–Max | 100–900 | 40–850 | 40–900 | |
| Pre-op Hb | ||||
| Mean±SD | 10.7±1.3 | 11.1±1.1 | 10.9 | 0.361b |
| Median | 10.6 | 11 | ||
| Min–Max | 7.8–13.9 | 8.3–13.9 | ||
| Post-op Hb | ||||
| Mean±SD | 10.7±1.4 | 11.4±2.3 | 11.1 | 0.133a |
| Median | 10.5 | 11.2 | ||
| Min–Max | 8.8–13 | 8–19.1 | ||
| Total | 44 | 44 | 88 | |
| a Mann-Whitney test, * b Independent test, * | ||||