15 May 2025 : Clinical Research
Effects of Remifentanil and Dexmedetomidine with Propofol on Laryngeal Mask Airway Insertion, Hemodynamic Stability, and Pharyngolaryngeal Morbidity: A Prospective Study of 80 Patients
Mensure Çakırgöz
ABCDEF 1*, İsmail Demirel ACDEF 2, Mert Akan CDE 3, Ergin Alaygut BCDE 1, Ömürhan Saraç BCDE 4, Aysun Afife Kar BCDEF 4, Büşra Emir CD 5, Derya Arslan Yurtlu CDEF 4
DOI: 10.12659/MSM.948186
Med Sci Monit 2025; 31:e948186
Table 5 Hemodynamic changes after induction.
| Time | Heart rate (bpm) | Systolic arterial blood pressure (mmHg) | ||||
|---|---|---|---|---|---|---|
| Group D (n=36) | Group R (n=37) | p value | Group D (n=36) | Group R (n=37) | p value | |
| Mean±SD | Mean±SD | Mean±SD | Mean±SD | |||
| Baseline | 79.39±12.85 | 78.57±10.76 | 0.768 | 139.83±16.15 | 141.38±12.35 | 0.647 |
| Before 1min | 63.17±9.93 | 68.89±9.87 | 127.22±13.34 | 116.14±7.37 | ||
| After 1 min | 64.11±9.93 | 69.68±9.85 | 123.00±12.72 | 114.84±7.19 | ||
| 2 min | 65.31±10.28 | 67.14±9.64 | 0.435 | 118.81±12.45 | 111.16±6.99 | |
| 3 min | 66.17±10.45 | 64.22±8.90 | 0.393 | 115.58±12.54 | 108.14±6.75 | |
| 4 min | 67.17±10.68 | 62.14±8.47 | 111.97±11.75 | 107.59±7.01 | 0.056 | |
| 5 min | 67.53±10.68 | 61.41±8.22 | 111.17±11.89 | 106.30±6.95 | ||
| Baseline | 100.17±11.24 | 101.46±9.50 | 0.597 | 80.31±11.61 | 81.51±10.50 | 0.642 |
| Before 1min | 91.81±10.18 | 82.19±6.31 | 74.08±10.86 | 65.24±7.61 | ||
| After 1 min | 89.25±9.85 | 82.43±5.96 | 72.36±10.61 | 66.14±7.60 | ||
| 2 min | 85.92±9.07 | 79.70±5.62 | 69.53±9.38 | 64.03±7.13 | ||
| 3 min | 82.81±8.93 | 76.81±5.10b | 66.53±9.21 | 61.22±6.36 | ||
| 4 min | 79.78±8.42 | 76.46±5.20 | 63.67±8.77 | 60.86±6.70 | 0.129 | |
| 5 min | 79.00±8.47 | 75.59±5.28 | 62.83±8.76 | 60.19±6.64 | 0.150 | |
| Group1: Propofol-Dexmedetomidine, Group 2: Propofol-Remifentanil. Group effect: p=0.961Time effect: Group*Time effect: repeated measures ANOVA results for Heart rate. Group effect: Time effect: Group*Time effect: repeated measures ANOVA results for Systolic arterial blood pressure. Group effect: Time effect: Group*Time effect: repeated measures ANOVA results for Mean arterial blood pressure. Group effect: Time effect: Group*Time effect: repeated measures ANOVA results for Diastolic arterial blood pressure. In comparing the time effect within the group, superscripts expressed with different letters indicate that there is a statistically significant. | ||||||