15 August 2025 : Clinical Research
Comparative Analysis of Hemodiafiltration Methods: Efficacy and Safety in Maintenance Hemodialysis
Zhuojia Xu ABCDEFG 1*, Dongdong Wang ABCDEF 1, Kai Wang BCDE 1, Guoyu Liang BCDE 1DOI: 10.12659/MSM.948227
Med Sci Monit 2025; 31:e948227
Table 4 Secondary outcome analysis: blood flow, transmembrane pressure (TMP), and convective volume completion rate (CVCR) in the 5 hemodiafiltration modalities.
| Variable (unit) | T1 | T2 | T3 | T4 | T5 |
|---|---|---|---|---|---|
| Blood flow (mL/min) | 262.58±19.73 | 265.19±19.49 | 264.07±17.82 | 259.26±19.79 | 261.48±15.62 |
| TMP 1 h (mmHg) | 108.96±22 | 199.11±41.11 | 184.56±29.88 | 174.15±16.36 | 212.67±32.8 |
| TMP 2 h (mmHg) | 119.3±22.71 | 219.7±41.42 | 202.22±33.94 | 188.44±26.94 | 231.22±44.31 |
| TMP 3 h (mmHg) | 128.26±26.39 | 222.63±39.47 | 202.11±25.13 | 201.04±34.53 | 238.11±52.43 |
| TMP 4 h (mmHg) | 137.22±27.75 | 222.48±34.88 | 210.59±40.35 | 203.59±31.61 | 251.81±46.38 |
| TMP mean (mmHg) | 123.44±27.08b | 215.98±40.7a | 199.87±34.31a | 191.81±30.69a | 233.45±46.95a |
| Actual convective volume (L) | 42.56±1.52 | 21.77±1.54 | 32.26±1.91 | 27.37±2.19 | 31.1±3.97 |
| CVCR (%) | 98.58±3.8b | 92.3±8.94a | 97.43±6.52b | 97.1±8.0b | 93.64±13.9a |
| Data are expressed as mean±standard deviation. All analyses were conducted using the Kruskal-Wallis non-parametric test. a b c d e | |||||