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29 August 2025 : Database Analysis  

Multimodal Neural Assessment for Predicting Post-Stroke Dysphagia: Identifying Critical Risk Factors Using Combined Indicators

Qian Zhang ACEF 1,2, Shuang Wu A 1,2*, Yangmei Shi BCD 2, Qian Chen BCD 2, Jiajie Gao BCD 2, Sijie Sun B 1, Jing Zhang B 1

DOI: 10.12659/MSM.948637

Med Sci Monit 2025; 31:e948637

Table 2 Comparison of continuous variables in baseline data between the 2 groups.

VariablesTotal (n=300)Non-dysphagia group (n=99)Dysphagia group (n=201)P value
Course (d, M(IQR))18.28 (12.98, 20.47)18.53 (12.22, 20.91)18.01 (13.21, 20.37)0.875
NIHSS (point, M(IQR))9.00 (7.00, 10.00)8.00 (6.50, 9.00)9.00 (8.00, 11.00)<0.001
Cp (M(IQR))0.46 (0.30, 0.54)0.47 (0.32, 0.76)0.46 (0.30, 0.51)0.012
PA (μV,M(IQR))85.58 (67.19, 100.83)95.44 (83.75, 108.06)76.66 (63.62, 94.11)<0.001
SD (s, M(IQR))1.45 (0.71, 2.04)1.46 (0.67, 1.85)1.44 (0.74, 2.22)0.040
ipsilateral MEP (μV, M(IQR))136.56 (108.06, 170.59)174.44 (154.82, 185.72)117.79 (97.40, 143.92)<0.001
contralateral MEP (μV, M(IQR))143.35 (109.49, 169.62)150.83 (128.49, 181.68)136.04 (102.54, 163.73)<0.001
RPFC (10/mmolmm, M(IQR))3.19 (3.05, 4.35)4.12 (3.10, 4.45)3.15 (3.04, 4.21)<0.001
RM1 (10/mmolmm, M(IQR))4.37 (3.30, 3.83)3.74 (3.47, 3.82)3.72 (3.24, 3.83)0.380
RS1 (10/mmolmm, M(IQR))3.52 (3.22, 3.62)3.53 (3.31, 3.64)3.49 (3.19, 3.61)0.021
LPFC (10/mmolmm, M(IQR))5.55 (4.55, 6.83)5.76 (4.70, 7.44)5.48 (4.44, 6.42)0.072
LM1 (10/mmolmm, M(IQR))3.98 (3.62, 4.61)3.99 (3.65, 4.96)3.96 (3.54, 4.39)0.068
LS1 (10/mmolmm, M(IQR))3.96 (3.57, 5.07)4.18 (3.75, 5.20)3.92 (3.48, 4.60)0.007
MPFC (10/mmolmm, M(IQR))6.00 (3.95, 7.89)6.04 (4.77, 8.36)5.55 (3.87, 7.67)0.070
NIHSS – National Institute of Health Stroke Scale; PA – peak amplitude; Cp – clustering coefficient; SD – swallowing duration; MEP – motor-evoked potentials; LPFC – left prefrontal cortex; RPFC – right prefrontal cortex; MPFC – middle dorsolateral prefrontal cortex; LM1 – left primary motor cortex; RM1 – right primary motor cortex; LS1 – left primary sensory cortex; RS1 – right primary sensory cortex; M – medians; IQR – interquartile ranges.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750