Multimodal Neural Assessment for Predicting Post-Stroke Dysphagia: Identifying Critical Risk Factors Using Combined Indicators

Qian Zhang; Shuang Wu; Yangmei Shi; Qian Chen; Jiajie Gao; Sijie Sun; Jing Zhang

doi:10.12659/MSM.948637

29 August 2025 : Database Analysis

Multimodal Neural Assessment for Predicting Post-Stroke Dysphagia: Identifying Critical Risk Factors Using Combined Indicators

Qian Zhang^{ACEF 1,2}, Shuang Wu^{A 1,2*}, Yangmei Shi^{BCD 2}, Qian Chen^{BCD 2}, Jiajie Gao^{BCD 2}, Sijie Sun^{B 1}, Jing Zhang^{B 1}

DOI: 10.12659/MSM.948637

Med Sci Monit 2025; 31:e948637

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Table 5 ROC evaluation of the predictive value of risk factors for PSD.

Variables	AUC	P value	95% CI	Best cut-off value	Sensitivity	Specificity	Youden index
NIHSS	0.663	<0.001	0.599~0.727	9.500	0.403	0.859	0.262
Cp	0.590	0.012	0.516~0.663	0.625	0.905	0.354	0.259
PA	0.709	<0.001	0.648~0.770	79.700	0.552	0.818	0.370
ipsilateral MEP	0.872	<0.001	0.833~0.911	141.635	0.736	0.889	0.625
contralateral MEP	0.651	<0.001	0.585~0.717	170.835	0.841	0.414	0.255
Cp+PA+ipsilateral MEP +contralateral MEP	0.985	<0.001	0.974~0.995	0.737	0.920	0.960	0.880
Cp+PA+ipsilateral MEP	0.939	<0.001	0.915~0.964	0.759	0.806	0.919	0.725
Cp+PA+contralateral MEP	0.794	<0.001	0.740~0.848	0.679	0.721	0.768	0.489
Cp+PA	0.744	<0.001	0.683~0.846	0.556	0.866	0.566	0.432
Cp+ipsilateral MEP	0.883	<0.001	0.846~0.921	0.717	0.776	0.869	0.645
Cp+contralateral MEP	0.679	<0.001	0.615~0.743	0.751	0.443	0.828	0.271
PA+ipsilateral MEP	0.934	<0.001	0.908~0.959	0.855	0.721	0.980	0.701
PA+contralateral MEP	0.766	<0.001	0.711~0.821	0.789	0.498	0.889	0.387
NIHSS – National Institute of Health Stroke Scale; Cp – clustering coefficient; PA – peak amplitude; MEP – motor-evoked potentials.

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Multimodal Neural Assessment for Predicting Post-Stroke Dysphagia: Identifying Critical Risk Factors Using Combined Indicators

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