29 October 2025 : Clinical Research
Diagnostic Value of Acoustic Analysis and Inflammation Markers in Pediatric Vocal Fold Nodules
Saime Güzelsoy SagirogluDOI: 10.12659/MSM.948789
Med Sci Monit 2025; 31:e948789
Table 4 Evaluation of diagnostic test performances of NLR, PLR, MPV, and SSI variables using ROC analysis.
| Sensitivity | Specificity | Cut-Off | AUC (95% CI) | p | |
|---|---|---|---|---|---|
| NLR | 0.667 | 0.667 | 1.18 | * | |
| PLR | 0.367 | 0.833 | 123.84 | 0.599 (0.455–0.743) | 0.188 |
| MPV | 0.800 | 0.367 | 9.25 | 0.503 (0.355–0.652) | |
| SSI | 0.733 | 0.600 | 358.98 | 0.647 (0.504–0.789) | |
| ROC curve; a: 0.05; AUC – area of the under curve; * the relevant biomarker provided a statistically significant distinction between the case and control groups. | |||||






