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29 October 2025 : Clinical Research  

Diagnostic Value of Acoustic Analysis and Inflammation Markers in Pediatric Vocal Fold Nodules

Saime Güzelsoy Sagiroglu ORCID logo ABCDEFG 1*

DOI: 10.12659/MSM.948789

Med Sci Monit 2025; 31:e948789

Table 4 Evaluation of diagnostic test performances of NLR, PLR, MPV, and SSI variables using ROC analysis.

SensitivitySpecificityCut-OffAUC (95% CI)p
NLR0.6670.6671.18*
PLR0.3670.833123.840.599 (0.455–0.743)0.188
MPV0.8000.3679.250.503 (0.355–0.652)
SSI0.7330.600358.980.647 (0.504–0.789)
ROC curve; a: 0.05; AUC – area of the under curve;
* the relevant biomarker provided a statistically significant distinction between the case and control groups.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750