26 August 2025 : Clinical Research
Radioactive Iodine Therapy for Pediatric Graves’ Hyperthyroidism
Rui-Ting Hu CDEF 1, Bin Li AB 2*DOI: 10.12659/MSM.948910
Med Sci Monit 2025; 31:e948910
Table 1 The baseline clinical characteristics of pediatric patients with GH.
| Variables | Range |
|---|---|
| Sex (Female/Male) | 34/10 |
| Mean age at diagnosis (years) | 15 (13.25, 16.75) |
| Mean age at RAI (years) | 17 (16, 18) |
| Duration of GH (months) | 12 (5, 36) |
| Family history of GH (yes/no) | 6/38 |
| Symptom and sign (yes/no) | 44/0 |
| Goiter | 39/5 |
| Palpitation | 28/16 |
| Tremors | 13/31 |
| Irritability | 19/25 |
| Hyperphagia | 12/32 |
| Comorbidity (yes/no) | 25/19 |
| Leukopenia | 9 |
| Abnormal liver function | 8 |
| Hypokalemic periodic paralysis | 4 |
| Atrial fibrillation | 0 |
| Two or more | 4 |
| ATD therapy history (yes/no) | 37/7 |
| Methimazole | 36 |
| Propylthiouracil | 0 |
| Both | 1 |
| None | 7 |
| Thyroid function before RAI (abnormal/normal) | 44/0 |
| Overt hyperthyroidism | 40 |
| Subclinical hyperthyroidism | 4 |






