Comparative Study of Ultrasound-Guided Corticosteroid Injection with Acupotomy Release Versus Injection Alone in Carpal Tunnel Syndrome: A Randomized Controlled Trial

19 September 2025 : Clinical Research

Song Tao^{CDEF 1}, Shiheng Xu^{BF 2}, Dantao Chu^{B 3}, Chenglin Zhu^{C 1}, Yanguan Bao^{AFG 4*}

DOI: 10.12659/MSM.948970

Med Sci Monit 2025; 31:e948970

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Table 2 Clinical outcomes at baseline and 2 weeks, 1 month, and 3 months after treatment.

Parameter	Group A (n=34)	Difference from baseline	Group B (n=34)	Difference from baseline	Inter-groupP value

Baseline	25.76±4.17^a		24.50±4.50^a
2 wk after tx	18.82±3.57^a	−6.94±3.03	18.12±3.09^a	−6.38±5.59	0.610
1 mo after tx	17.26±3.45^b	−8.50±4.83	19.00±4.01^b	−5.50±5.24	0.017
3 mo after tx	17.47±3.31^c	−8.29±4.83	20.85±3.99^c	−3.65±4.45	0.000

Baseline	12.26±3.67^a		11.91±3.37^a
2 wk after tx	11.50±3.42^a	−0.76±1.07	11.12±2.85^a	−0.79±0.98	0.906
1 mo after tx	10.91±3.44^b	−1.35±1.35	11.15±2.96^b	−0.76±0.92	0.039
3 mo after tx	10.35±3.21^c	−1.91±1.52	11.24±2.84^c	−0.68±1.12	0.000

Baseline	15.31±2.96^a		14.33±2.41^a
3 mo after tx	11.63±2.80^a	−3.68±3.22	12.58±2.16^a	−1.75±2.68	0.009

Baseline	3.57±0.54^a		3.49±0.45
3 mo after tx	3.30±0.45^a	−0.27±0.37	3.42±0.39	−0.06±0.43	0.038
BCTQ-S – Boston Carpal Tunnel Questionnaire-Symptom Severity Score; BCTQ-F – Boston Carpal Tunnel Questionnaire-Functional Status Scale; CSA – cross-sectional area; tx – treatment; wk – week; mo – month. Significant differences within the same group: ^a between baseline and 2-week post-tx scores; ^b between baseline and 1-month post-tx scores; ^c between baseline and 3-month post-tx scores; ^d between 2-week and 1-month post-tx scores; ^e between 2-week and 3-month post-tx scores; ^F between 1-month and 3-month post-tx scores.

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