15 September 2025 : Clinical Research
Optimizing Ventilation Strategies to Reduce Pulmonary Complications in Frail Patients: A Comparative Study
Yang Cao AEG 1,2, Enci Liu CD 3, Yongling Xu AD 1, Changzheng Shangguan F 4, Mengxia Ge B 1, Changzheng Yuan AB 1, Baohui Xia A 1, Bo Zhang D 1, Di Gao B 1, Wangning Shangguan AE 2*, Juan Chen E 5DOI: 10.12659/MSM.948977
Med Sci Monit 2025; 31:e948977
Table 3 Arterial blood gas and oxygenation index at different time points.
| Variable (mmHg) | ΔP group (n=31)** | N group (n=30)** | t-value*** | P value |
|---|---|---|---|---|
| PaO-T0 | 156.3±39.5 | 176.2±37.6 | −2.02 | 0.048 |
| PaO-T1 | 173.7±38.5 | 166.1±34.3 | 0.81 | 0.423 |
| PaO-T2 | 184.1±36.0 | 167.4±32.9 | 1.88 | 0.066 |
| PaO-T3 | 112.5±29.4 | 101.2±35.9 | 1.33 | 0.188 |
| OI-T0 | 313±79 | 349±78 | −1.79 | 0.078 |
| OI-T1 | 347±77 | 333±69 | 0.78 | 0.440 |
| OI-T2 | 368±72 | 335±66 | 1.87 | 0.066 |
| OI-T3 | 378±68 | 349±60 | 1.71 | 0.093 |
| PaO – partial pressure of arterial oxygen; OI – oxygenation index, calculated as PaO/FiO; T0 – immediately after intubation; T1 – after 60 minutes of positive end-expiratory pressure titration; T2 – end of surgery; T3 – 24 hours after surgery. ** Values are presented as mean±SD. *** Paired Student’s t-test was used for within-group comparisons at different time points. **** | ||||