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25 June 2025 : Clinical Research  

Differentiating Between Methylphenidate Use and Misuse: Clinical Insights From University Students and Academic Staff in Türkiye

Meltem Gürü ABCDEFG 1*

DOI: 10.12659/MSM.948984

Med Sci Monit 2025; 31:e948984

Table 2 Most frequent psychiatric and medical comorbidities among ındividuals seeking methylphenidate (n=135), by ADHD diagnosis and misuse pattern.

Group/variablePsychiatric comorbiditiesReported medical comorbidities
ADHD-diagnosed misusers (n=4)Cannabis use disorder (n=3, 75.0%)Alcohol use disorder (n=2, 50.0%)Tic disorder (n=1, 25.0%)Severe obesity (n=1, 25.0%)
ADHD-diagnosed non-misusers (n=45)Generalized anxiety disorder (n=10, 22.2%)Obsessive-compulsive disorder (n=5, 11.1%)Major depressive disorder (n=3, 6.7%)Severe obesity (n=4, 8.9%)
Non-ADHD misusers (n=16)None (n=7, 43.8%)Alcohol use disorder (n=5, 31.2%)Generalized anxiety disorder (n=5, 31.2%)None
Non-ADHD non-misusers (n=70)Generalized anxiety disorder (n=26, 37.1%)Major depressive disorder (n=23, 32.9%)None (n=22, 31.4%)Hypertension (n=1, 1.4%)
ADHD – attention deficit hyperactivity disorder. Psychiatric comorbidities were identified excluding ADHD as a primary diagnosis. “None” indicates absence of any additional psychiatric diagnosis or reported medical comorbidity. Individuals may have more than 1 diagnosis; therefore, the sum of n or% may exceed group totals.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750