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25 June 2025 : Clinical Research  

Differentiating Between Methylphenidate Use and Misuse: Clinical Insights From University Students and Academic Staff in Türkiye

Meltem Gürü ABCDEFG 1*

DOI: 10.12659/MSM.948984

Med Sci Monit 2025; 31:e948984

Table 3 Clinical and behavioral distinctions between ADHD and non-ADHD ındividuals seeking methylphenidate (n=135).

Variable/groupADHDn (%)Non-ADHDn (%)P value
Median age (min–max)22 (18–33)25 (19–55)
GenderFemale22 (44.9%)40 (46.5%)0.5
Male27 (55.1%)46 (53.5%)
Educational LevelUniversity42 (85.7%)49 (57%)
Master’s6 (12.2%)17 (19.8%)
PhD or higher1 (2%)20 (23.3%)
Repeating a srade20 (40.8%)35 (40.7%)0.566
Median age of onset for attention deficit14 (5–20)20 (15–45)
Median age of First MPH use15 (7–24)23 (18–30)
Psychiatric comorbidity31 (63.3%)58 (67.4%)0.706
Cigarette smoking22 (45.0%)56 (65.0%)
Alcohol and substance use disorder2 (4%)11 (12.8%)0.085
Presence of psychiatric disorders in the family34 (69.4%)18 (21%)
MedicationShort-acting MPH10 (20.4%)63 (73.3%)
Intermediate-acting MPH15 (30.6%)0 (0%)
Long-acting MPH16 (32.7%)14 (16.2%)
Multiple MPH formulations8 (16.3%)9 (10.5%)
Follow-up attendance46 (93.9%)28 (32.6%)*
* Fisher’s exact test was used for categorical comparisons when expected cell counts were low.
ADHD – attention deficit hyperactivity disorder; min – minimum; max – maximum; PhD – Doctor of Philosophy; MPH – methylphenidate.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750