Anterior Capsular Contraction Syndrome in Cataract Surgery: A Review of Challenges and Solutions

12 September 2025 : Review article

Peng Lan^{E 1}, Lili Nie^{E 1}, Liangliang Zhao^{A 1*}

DOI: 10.12659/MSM.949046

Med Sci Monit 2025; 31:e949046

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Definition and Clinical Features Causes and Influential Factors Preventative Strategies Therapeutic Interventions Conclusions References

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Table 1 Recent advances in therapeutic interventions for capsule contraction syndrome.

Treatment option	Key findings	Reference
Invasive surgical treatment options	Significant improvement in postoperative visual acuity after capsular bag relaxing surgery; effective in severe fibrosis cases	[]⁹⁶
Invasive surgical treatment options	Risks including potential vision interference and corneal endothelium damage; radial incision method preferred	[]⁹⁹
Noninvasive laser treatment	Modified C-type neodymium-doped yttrium aluminum garnet (YAG) laser capsulotomy technique for fibrous tissue proliferation; lower postoperative complications	[]¹⁰⁰
	Ring YAG laser was more effective in capsular bag contraction relief than radial YAG laser; safer approach	[]¹⁰⁹
	Femtosecond laser-assisted capsulotomy for capsular bag crumpling; stability in crystalline position was observed	[]¹¹⁰

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