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09 July 2025 : Clinical Research  

Performance of AI Chatbots in Preliminary Diagnosis of Maxillofacial Pathologies

Ridvan Guler ORCID logo ABDEF 1*, Emine Yalcin ORCID logo BCEF 1

DOI: 10.12659/MSM.949076

Med Sci Monit 2025; 31:e949076

Table 1 Answers given by chatbots for preliminary diagnosis of each cyst case.

What is the most probable preliminary diagnosis based on the radiographic images?
CaseOptions for preliminary diagnosisChatbots answers
ChatGPTGrokBlackbox AIClaude AI
1B. Central giant cell granulomaC. KeratocystD. Radicular cyst* * Keratocyst* *
2A. KeratocystB. AmeloblastomaC. Dentigerous cyst* KeratocystAmeloblastoma* Ameloblastoma
3A. Nasopalatine duct cystB. Radicular cystC. Aneurysmal bone cyst* * * * Radicular cyst
4A. Dentigerous cystB. AmeloblastomaC. Radicular cyst* Dentigerous cystAmeloblastoma* Ameloblastoma
5A. KeratocystB. AmeloblastomaC. Radicular cyst* * * Keratocyst*
6A. Radicular cystB. Central mucoepidermoid carsinomaD. Keratocyst* Radicular cystRadicular cyst* *
7A. Radicular cystC. KeratocystD. Ameloblastoma* AmeloblastomaAmeloblastomaKeratocystAmeloblastoma
8B. Simple bone cystC. Basal cell nevus syndromeD. Traumatic bone cyst* * * * *
9A. Radicular cystC. Nazolabial kistD. Globulomaxillary cyst* * * Radicular cystRadicular cyst
* Correct answer.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750