12 November 2025 : Animal Research
[Retracted: 19 Feb 2026] Xiehuang San Extract Attenuates Insulin Resistance in Obese Rats via Gut Microbiota Modulation: Experimental Evidence
YuXin Yang ABCDEF 1, Yantong Liu EF 2, Gui-Ju Zhang EFG 1*DOI: 10.12659/MSM.949151
Med Sci Monit 2025; 31:e949151
Table 1 Experimental grouping and treatment schedule.
| Group name | N | Diet | Treatment | Dose (g/mL/day) | Route |
|---|---|---|---|---|---|
| Control | 5 | Standard chow | Saline | – | Oral gavage |
| Model | 5 | High-fat diet | Saline | – | Oral gavage |
| XHS-L | 5 | High-fat diet | XHS | 0.256 | Oral gavage |
| XHS-M | 5 | High-fat diet | XHS | 0.513 | Oral gavage |
| XHS-H | 5 | High-fat diet | XHS | 1.026 | Oral gavage |
| Metformin | 5 | High-fat diet | Metformin | 0.8 | Oral gavage |
| XHS – Xiehuang San; XHS-L – Xiehuang San low-dose group; XHS-M – Xiehuang San medium-dose group; XHS-H – Xiehuang San high-dose group. | |||||
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