Advances in Positron Emission Tomography/Computed Tomography for Diagnosing and Managing Primary Posterior Uveal Melanoma

19 August 2025 : Review article

Iwona Obuchowska

^{ABCDEF 1}, Diana Anna Dmuchowska

^{DE 1}, Joanna Konopińska

^{EF 1*}

DOI: 10.12659/MSM.949252

Med Sci Monit 2025; 31:e949252

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Introduction Posterior Uveal Melanoma Positron Emission Tomography Role of PET/CT in the Detection of Posterior Uveal Melanoma Role of PET/CT Imaging in Distinguishing Between Posterior Uveal Melanomas, Benign Lesions and Other Primary or Metastatic Intra-Ocular Malignancies Role of PET/CT in Staging of Metastatic Uveal Melanoma Monitoring of Treatment Outcomes in Posterior Uveal Melanoma with PET/CT Limitations of PET/CT Imaging Future Directions Conclusions References

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Table 1 The AJCC* cancer staging system for posterior uveal melanoma (choroidal and ciliary body) in regard to size – T category (T1–T4).

Thickness (mm)
>15.0	4	4	4	4	4	4	4
12.1–15.0	3	3	3	3	3	4	4
9.1–12.0	3	3	3	3	3	3	4
6.1–9.0	2	2	2	2	3	3	4
3.1–6.0	1	1	1	2	2	3	4
≤.0	1	1	1	1	2	2	4
	≤3.0	3.1–6.0	6.1–9.0	9.1–12.0	12.1–15.0	15.1–18.0	>18.0

^* AJCC – American Joint Committee on Cancer. Source: .

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