19 August 2025 : Review article
Advances in Positron Emission Tomography/Computed Tomography for Diagnosing and Managing Primary Posterior Uveal Melanoma
Iwona Obuchowska
ABCDEF 1, Diana Anna Dmuchowska DE 1, Joanna Konopińska EF 1*
DOI: 10.12659/MSM.949252
Med Sci Monit 2025; 31:e949252
Introduction
Posterior Uveal Melanoma
Positron Emission Tomography
Role of PET/CT in the Detection of Posterior Uveal Melanoma
Role of PET/CT Imaging in Distinguishing Between Posterior Uveal Melanomas, Benign Lesions and Other Primary or Metastatic Intra-Ocular Malignancies
Role of PET/CT in Staging of Metastatic Uveal Melanoma
Monitoring of Treatment Outcomes in Posterior Uveal Melanoma with PET/CT
Limitations of PET/CT Imaging
Future Directions
Conclusions
References
Table 4 The AJCC* cancer staging system for posterior uveal melanoma (choroidal and ciliary body) – characteristics of stage group from I to IV.
| When T is… | When N is… | When M is… | Then the stage group is… |
|---|---|---|---|
| T1a | N0 | M0 | I |
| T1b-d | N0 | M0 | IIA |
| T2a | N0 | M0 | IIA |
| T2b | N0 | M0 | IIB |
| T3a | N0 | M0 | IIB |
| T2c-d | N0 | M0 | IIIA |
| T3b-c | N0 | M0 | IIIA |
| T4a | N0 | M0 | IIIA |
| T3d | N0 | M0 | IIIB |
| T4b-c | N0 | M0 | IIIB |
| T4d-e | N0 | M0 | IIIC |
| Any T | N1 | M0 | IV |
| Any T | N1 | M1a-c | IV |
| * AJCC – American Joint Committee on Cancer. Source: . | |||