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16 November 2025 : Review article  

Association of Childhood Asthma with the Concept of Exposomics: A Short Review

Martyna Pajewska-Szmyt ORCID logo BDEF 1, Agnieszka Klupczyńska-Gabryszak ORCID logo ADE 1, Joanna Matysiak ORCID logo E 2, Timothy J. Garrett ORCID logo E 3, Jan Matysiak ORCID logo ADE 1*

DOI: 10.12659/MSM.949589

Med Sci Monit 2025; 31:e949589

Table 1 Characterization of potential environmental pollution (potential source and pathways of exposure), which can be correlated with asthma.

Environmental pollutionPotential sourceKey characteristicsPathways of human exposureCorrelation with asthmaReferences
DBP, DiBP, DEP[–]80
Low molecular weight PAHsHigh molecular weight PAHs[–]85
PFOA, PFOS[–]90
[–]97
PAEs – phthalate esters; DBP – dibutyl phthalate; DiBP – diisobutyl phthalate; DEP – diethyl phthalate; FeNO – Fractional Exhaled Nitric Oxide; PAHs – polycyclic aromatic hydrocarbons; PM – particulate matter; 1-OHPyr – 1 hydroxypyrene; PFAS – per and polyfluoroalkyl substances; PFOA – perfluorooctanoic acid; PFOS – perfluorooctane sulfonate; PFCs – perfluorinated compounds; PFUnDA – perfluoroundecanoic acid; Me-PFOSA-AcOH – 2-(N-Methyl-perfluorooctane sulfonamido) acetic acid; PFDA – perfluorodecanoic acid; SHS – secondhand smoke.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750