11 November 2025 : Clinical Research
Effect of Anesthesia on Functional Outcomes in Acute Ischemic Stroke Patients Undergoing Thrombectomy with the RECO Device
Yunlong Ding
ABEFG 1,2, Jiali Niu ACDE 3, Kai Dong BDE 4, Tingting Zhai BE 1, Yanrong Zhang BE 1, Wenjuan Wang BE 1, Hongjun Chen ADE 2,5, Yan Liu AEF 1*
DOI: 10.12659/MSM.949605
Med Sci Monit 2025; 31:e949605
Table 3 Risk factors associated with poor outcome at 90 days in patients with AIS with LVO.
| Items | Poor outcome (n=135) | Good outcome (n=131) | P | Adjusted OR (95% CI) | Adjusted P |
|---|---|---|---|---|---|
| Male | 74/135 (54.8) | 90/131 (68.7) | 0.020 | 0.754 (0.418–1.361) | 0.349 |
| Age, y | 71 (61,76) | 66 (57,75) | 0.037 | 1.015 (0.990–1.041) | 0.244 |
| Smoking | 0.473 | ||||
| Never | 102/123 (82.9) | 92/120 (76.7) | |||
| Current | 19/123 (15.4) | 25/120 (20.8) | |||
| Recent | 2/123 (1.6) | 3/120 (2.5) | |||
| Drinking status | 0.624 | ||||
| Never | 111/130 (85.4) | 104/129 (80.6) | |||
| Occasionally | 9/130 (6.9) | 13/129 (10.1) | |||
| Current | 8/130 (6.2) | 11/129 (8.5) | |||
| Recent | 2/130 (1.5) | 1/129 (0.8) | |||
| Hypertension | 92/132 (69.7) | 82/129 (63.6) | 0.293 | ||
| Diabetes | 24/132 (18.2) | 13/128 (10.2) | 0.064 | 1.839 (0.832–4.068) | 0.132 |
| Hyperlipidemia | 1/132 (0.8) | 1/129 (0.8) | 0.987 | ||
| Previous stroke | 32/133 (24.1) | 25/129 (19.4) | 0.359 | ||
| Coronary heart disease | 21/132 (15.9) | 13/128 (10.2) | 0.169 | ||
| Atrial fibrillation | 46/133 (34.6) | 50/129 (38.8) | 0.483 | ||
| TIA | 5/133 (3.8) | 2/129 (1.6) | 0.268 | ||
| Cerebral hemorrhage | 2/132 (1.5) | 0/129 (0) | 0.160 | ||
| Heart valve disease | 7/131 (5.3) | 5/129 (3.9) | 0.573 | ||
| TOAST classification | 0.374 | ||||
| Large atherosclerotic stroke | 30/82 (36.6) | 40/104 (38.5) | |||
| Cardiogenic cerebral embolism | 51/82 (62.2) | 58/104 (55.8) | |||
| Other stroke with definite aetiology | 0/82 (0) | 2/104 (1.9) | |||
| Stroke of unknown aetiology | 1/82 (1.2) | 4/104 (3.8) | |||
| Inter-hospital transfer | 47/135 (34.8) | 30/131 (22.9) | 0.032 | 1.219 (0.644–2.309) | 0.543 |
| Initial NIHSS | 19 (16,25) | 15 (11,20) | 0.000 | 1.079 (1.037–1.123) | <0.001 |
| IVT | 20/135 (14.8) | 39/131 (29.8) | 0.003 | 0.548 (0.277–1.082) | 0.083 |
| Final mTICI (2b-3) | 126/132 (95.5) | 128/131 (97.7) | 0.314 | ||
| GA | 62/135 (45.9) | 85/131 (64.9) | 0.002 | 0.557 (0.311–1.000) | 0.050 |
| Onset-to-door time, min (n=133/130) | 150 (69,287) | 120 (67,255) | 0.394 | ||
| Onset-to-puncture time, min (n=133/130) | 275 (170,378) | 230 (158,380) | 0.111 | ||
| Onset-to-recanalization time, min (n=127/126) | 345 (257,475) | 310 (212,449) | 0.039 | 1.000 (1.000–1.001) | 0.667 |
| Puncture-to-recanalization time, min (n=128/126) | 66 (45,101) | 59 (44,84) | 0.107 | ||
| Door-to-puncture time, min (n=133/130) | 101 (79,120) | 92 (72,116) | 0.109 | ||
| Risk factors associated with poor outcome at 90 days in patients with AIS with LVO. AIS – acute ischemic stroke; LVO – large-vessel occlusion; OR – odds ratio; TIA – transient ischemic attack; TOAST – trial of org 10172 in acute stroke treatment; NIHSS – National Institutes of Health Stroke Scale; IVT – intravenous thrombolysis; mTICI – modified thrombolysis in cerebral infarction; GA – general anesthesia. | |||||