02 November 2025 : Clinical Research
Maternal Serum Galectin-1 in the First Trimester as a Potential Biomarker for Early Prediction of Pre-Eclampsia: A Prospective Study
Zhiling Yang BCE 1, Meilin Li AEFG 1, Caifeng Deng ABG 1, Chaolin Huang CDF 1*, Lingjiao Wu CDE 1DOI: 10.12659/MSM.949822
Med Sci Monit 2025; 31:e949822
Table 4 Predictive performance of galectin-1 for pre-eclampsia.
| Biomarkers | AUC (95% CI) | Sensitivity | Specificity | Cutoff value (ng/ml) | p-value |
|---|---|---|---|---|---|
| Galectin-1 | 0.84 (0.65–0.94) | 82.32% | 78.47% | 34.42 | |
| sFlt-1 | 0.73 (0.51–0.87) | 73.45% | 65.34% | 63.58 | |
| PlGF | 0.64 (0.41–0.72) | 62.54% | 61.62% | 32.52 | |
| Predictive performances of galectin-1 for pre-eclampsia were assessed by receiver operating characteristic curve analyses. A p | |||||