02 November 2025 : Clinical Research
Maternal Serum Galectin-1 in the First Trimester as a Potential Biomarker for Early Prediction of Pre-Eclampsia: A Prospective Study
Zhiling Yang BCE 1, Meilin Li AEFG 1, Caifeng Deng ABG 1, Chaolin Huang CDF 1*, Lingjiao Wu CDE 1DOI: 10.12659/MSM.949822
Med Sci Monit 2025; 31:e949822
Table 5 Predictive performance of galectin-1 for early-onset and late-onset pre-eclampsia.
| Biomarkers | AUC (95% CI) | Sensitivity | Specificity | Cutoff value (ng/ml) | p-value |
|---|---|---|---|---|---|
| Early-onset | 0.91 (0.73–0.98) | 88.56% | 85.27% | 32.41 | |
| Late-onset | 0.76 (0.51–0.84) | 75.64% | 72.41% | 34.31 | |
| Predictive performances of galectin-1 for early-onset and late-onset pre-eclampsia were assessed by receiver operating characteristic curve analyses. A p | |||||