Machine Learning Analysis of Retrospective Data From 503 Hospitalized Older Patients With Type 2 Diabetes to Identify Factors Associated With Cognitive Impairment

10 January 2026 : Laboratory Research

Mingzhu Yu^{ABCDEFG 1,2*}, Jianfeng Zhang^{A 1}, Haigeng Chen^{A 3}, Guiyue Li^{A 4}

DOI: 10.12659/MSM.949864

Med Sci Monit 2026; 32:e949864

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Table 3 Multivariable logistic regression analysis of risk factors for mild cognitive impairment.

Predictor	Odds ratio	95% Confidence interval	P-value
Age	1.12	1.07–1.18	<0.001
Body mass index	1.05	1.01–1.09	0.016
Glycated hemoglobin (HbA1c)	1.13	1.04–1.24	0.007
C-reactive protein	1.08	1.02–1.15	0.012
Waist-to-height ratio	1.20	0.95–1.52	0.125
Diabetic complications	3.50	1.8–6.82	<0.001
Diabetes duration exceeding 5 years	2.10	1.2–3.68	0.010
Low education level	0.75	0.55–0.98	0.050
().

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