19 February 2026 : Clinical Research
Efficacy of Nano-Carbon Tracing Versus Indocyanine Green in Lymph Node Detection for Minimally Invasive Colorectal Resection
Pei Yang ABCDEF 1, Rui Bao ABCDEF 2, Yang He ABCDEF 1, Yongjiang Zhao CDE 3, Yao Wang CDE 4, Yongliang Yao ACDEF 3*DOI: 10.12659/MSM.949967
Med Sci Monit 2026; 32:e949967
Table 1 Baseline patient characteristics with effect sizes.
| Baseline characteristics | Nano-carbon labeling group (n=100)* | Control group (n=100)* | P-value | Effect size (95% Confidence interval) |
|---|---|---|---|---|
| Age (years) | 61.32±9.28 | 60.15±10.43 | 0.563 | MD=+1.17 (−2.9 to +5.2) |
| Sex (Male/Female) | 56/44 (56.0%/44.0%) | 52/48 (52.0%/48.0%) | 0.702 | RD=+4% male (−12% to +20%) |
| BMI (kg/m) | 24.75±3.61 | 25.10±4.02 | 0.481 | MD=−0.35 (−1.4 to +0.7) |
| Tumor location | 0.639 | RD=colon −4% (−20% to +12%) | ||
| Colon | 64 (64.0%) | 68 (68.0%) | ||
| Rectum | 36 (36.0%) | 32 (32.0%) | ||
| Tumor stage (TNM) | 0.582 | RD=similar distribution, NS | ||
| T1 | 12 (12.0%) | 16 (16.0%) | ||
| T2 | 28 (28.0%) | 26 (26.0%) | ||
| T3 | 44 (44.0%) | 42 (42.0%) | ||
| T4 | 16 (16.0%) | 16 (16.0%) | ||
| Medical history | 0.732 | RD=diabetes −4% (−16% to +8%) | ||
| Diabetes | 20 (20.0%) | 24 (24.0%) | ||
| Hypertension | 30 (30.0%) | 26 (26.0%) | ||
| Others | 14 (14.0%) | 18 (18.0%) | ||
| Preoperative imaging | 0.445 | MD=−0.14 cm (−0.6 to +0.3) | ||
| Tumor size (cm) | 4.56±1.24 | 4.70±1.37 | ||
| * Data are presented as mean±standard deviation or n (%). BMI – body mass index; MD – mean difference; NS – not significant; RD – risk difference; TNM – tumor-node-metastasis. | ||||