28 October 2025 : Clinical Research
Effect of Mitral Isthmus Ablation on Recurrence Rates in High-Burden Paroxysmal Atrial Fibrillation
Luqian Cui ABCDEF 1, Hailan Wang BDEF 2, Jingchao Li AE 3, Haijia Yu E 3, Huihui Song BE 3, Yingjie Chu AEG 3, Shujuan Dong AE 3*DOI: 10.12659/MSM.950108
Med Sci Monit 2025; 31:e950108
Table 1 Baseline clinical characteristics of the 2 groups.
| Characteristic | Overall population | 2C1L group (n=51) | 2C group (n=102) | P value |
|---|---|---|---|---|
| Age (y) | 61.0±10.0 | 60.2±9.8 | 61.4±10.1 | 0.493 |
| Sex: female | 41 (26.8%) | 14 (27.5%) | 27 (26.5%) | 0.897 |
| AF duration (y) | 4.0 (2.0, 6.0) | 5.0 (2.0, 5.0) | 4.0 (2.0, 6.0) | 0.880 |
| Congestive heart failure | 18 (11.8%) | 5 (9.8%) | 13 (12.7%) | 0.595 |
| Hypertension | 54 (35.3%) | 20 (39.2%) | 34 (33.3%) | 0.473 |
| Diabetes | 17 (11.1%) | 6 (11.8%) | 11 (10.8%) | 0.856 |
| Stroke | 10 (6.5%) | 3 (5.9%) | 7 (6.9%) | 1.000 |
| Vascular disease | 20 (13.1%) | 6 (11.8%) | 14 (13.7%) | 0.734 |
| CHA2DS2-VASc score | 1.0 (0.5, 2.5) | 1.0 (0.0, 2.0) | 1.0 (0.8, 3.0) | 0.740 |
| LAD (mm) | 41.9±4.6 | 42.2±4.9 | 41.7±4.4 | 0.502 |
| LVEF (%) | 62.8±5.0 | 62.4±5.3 | 63.0±4.9 | 0.532 |
| AF – atrial fibrillation; CHA2DS2-VASc – congestive heart failure, hypertension, age ≥75 years, diabetes mellitus, stroke/transient ischemic attack/thromboembolism, vascular disease, age 65 to 74 years, sex category (female); LAD – left atrial diameter; LVEF – left ventricular ejection fraction. | ||||