31 October 2025 : Clinical Research
Comparative Oncologic Outcomes in High-Risk Human Papillomavirus-Positive and -Negative Cervical Intraepithelial Neoplasia
Saliha Sağnıç
ABCDEF 1*, Serap Fırtına Tuncer ABCF 2, Hasan Aykut Tuncer CDF 1, Selen Doğan ADF 1, Tayup Şimşek ADF 1
DOI: 10.12659/MSM.950452
Med Sci Monit 2025; 31:e950452
Table 2 Comparison of clinical characteristics between patients with and without recurrence.
| Characteristics | No recurrence (n=467) | Recurrence (n=65) | P value |
|---|---|---|---|
| 38.0 (11.0) | 41.0 (9.0) | ||
| 24.1 (5.5) | 24.2 (6.4) | 0.506 | |
| 2.0 (2.0) | 2.0 (2.0) | ||
| 2.0 (1.0) | 2.0 (2.0) | ||
| 0.279 | |||
| NVD | 241 (51.6) | 37 (56.9) | |
| CS | 88 (18.8) | 13 (20.0) | |
| NVD+CS | 42 (9) | 8 (12.3) | |
| None | 96 (20.6) | 7 (10.8) | |
| 0.236 | |||
| No | 406 (86.9) | 53 (81.5) | |
| Yes | 61 (13.1) | 12 (18.5) | |
| 0.262 | |||
| No | 429 (91.9) | 57 (87.7) | |
| Yes | 38 (8.1) | 8 (12.3) | |
| 0.169 | |||
| Ever smoked | 272 (58.2) | 32 (49.2) | |
| Never smoked | 195 (41.8) | 33 (50.8) | |
| None | 216 (46.3) | 34 (52.3) | 0.359 |
| Using | 251 (53.7) | 31 (47.7) | |
| 0.220 | |||
| Positive | 415 (88.9) | 61 (12.1) | |
| Negative | 52 (11.1) | 4 (6.2) | |
| 0.578 | |||
| Negative | 371 (79.4) | 54 (83.1) | |
| Positive | 90 (19.3) | 11 (16.9) | |
| Unassessable | 6 (1.3) | 0 (0) | |
| 0.386 | |||
| Follow-up | 431 (92.3) | 57 (87.7) | |
| Re-conization | 35 (7.5) | 8 (12.3) | |
| Hysterectomy | 1 (0.2) | 0 (0) | |
| IQR – interquartile range; BMI – body mass index; NVD – normal vaginal delivery; CS – cesarean section; HPV – human papillomavirus. | |||